{"id":"W2078847227","doi":"10.1016/j.virusres.2006.10.009","title":"Role of envelope processing and gp41 membrane spanning domain in the formation of human immunodeficiency virus type 1 (HIV-1) fusion–competent envelope glycoprotein complex","year":2006,"lang":"en","type":"article","venue":"Virus Research","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"","keywords":"Gp41; Ectodomain; Biology; Glycoprotein; Lipid bilayer fusion; Viral entry; Mutant; Herpesvirus glycoprotein B; Viral envelope; Infectivity; Virology; Transmembrane protein; Cell fusion; Cell biology; Virus; Molecular biology; Viral replication; Biochemistry; Receptor; Cell; Epitope; Antibody; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003311871,0.0004032854,0.0002822301,0.000228206,0.0006073308,0.0008327767,0.0003359527,0.0009109795,0.001198062],"category_scores_gemma":[0.0005278657,0.0003029191,0.000425026,0.0001317364,0.0003400007,0.0009731292,0.000476656,0.0007550066,0.0007153227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004817838,"about_ca_system_score_gemma":0.0003692382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003905515,"about_ca_topic_score_gemma":0.0002057179,"domain_scores_codex":[0.9998233,0.00003239153,0.00001476338,0.00003784441,0.00003522062,0.0000565038],"domain_scores_gemma":[0.9997444,0.00008608255,0.00004015024,0.00003689664,0.00002831366,0.000064158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003559451,0.00006003629,0.0003197674,0.00004946822,0.0000071957,0.0004996581,0.00007462096,0.0001679659,0.9958932,0.001127009,0.00007630229,0.00136877],"study_design_scores_gemma":[0.00003738824,0.0001445027,0.004664353,0.000008464416,0.00001341708,0.001261949,0.00007623528,0.002028006,0.9895139,0.0003957315,0.001843882,0.00001213888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948041,0.0012143,0.002134358,0.000171072,0.00003214672,0.00002827091,0.00009076938,0.0000413858,0.001483681],"genre_scores_gemma":[0.9952731,0.0003179253,0.002226886,0.00007533448,0.00001139345,0.00001371013,0.0004391942,0.00002102351,0.001621566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001198062,"threshold_uncertainty_score":0.004007876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04938301260614323,"score_gpt":0.3293576955680759,"score_spread":0.2799746829619326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}