{"id":"W2078901418","doi":"10.1038/sj.gt.3302486","title":"Combined CD4+ Th1 effect and lymphotactin transgene expression enhance CD8+ Tc1 tumor localization and therapy","year":2005,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Transgene; CD8; Biology; Cytotoxic T cell; Adoptive cell transfer; Genetic enhancement; Ovalbumin; Cancer research; T cell; T-cell receptor; Immunotherapy; Molecular biology; Immunology; Cell therapy; Cell; Immune system; In vitro; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003047496,0.0007515695,0.0006989297,0.0008710233,0.0002634364,0.0005815721,0.0003457265,0.000613585,0.00288921],"category_scores_gemma":[0.000165259,0.0002703036,0.0003787832,0.000346047,0.0004202412,0.0005098087,0.0003789369,0.001287172,0.0005850956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000500751,"about_ca_system_score_gemma":0.000415882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008337108,"about_ca_topic_score_gemma":0.001646702,"domain_scores_codex":[0.9995859,0.00006473492,0.00002545617,0.00008092707,0.0001002102,0.0001427287],"domain_scores_gemma":[0.9998243,0.00004829631,0.00003772878,0.00003037432,0.00001732184,0.00004195108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002168222,0.00009681491,0.00008188297,0.00003915595,0.000007505528,0.00002291504,0.00001390308,0.0001718887,0.9966969,0.0002444049,0.00004777727,0.002359982],"study_design_scores_gemma":[0.00005614619,0.0003954028,0.0004701434,0.000003365492,0.00002594365,0.00008930935,0.000009287851,0.0008312367,0.9966222,0.00005510503,0.001438441,0.000003439452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818919,0.002597274,0.009948308,0.0001781986,0.00008818886,0.0001438252,0.000259076,0.0004008811,0.004492357],"genre_scores_gemma":[0.9910085,0.0004781728,0.004512679,0.0000490103,0.00003738255,0.00008841959,0.0001159975,0.00005487124,0.003655155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00288921,"threshold_uncertainty_score":0.00966537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007303783084616129,"score_gpt":0.2399381580456141,"score_spread":0.232634374960998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}