{"id":"W2078909289","doi":"10.1016/j.jconrel.2005.06.001","title":"Effects of lipid segregation and lysolipid dissociation on drug release from thermosensitive liposomes","year":2005,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"ca_institutions":"Celator Pharmaceuticals (Canada); University of British Columbia; BC Cancer Agency","funders":"","keywords":"Liposome; Chemistry; Vesicle; Phosphatidylcholine; Bilayer; Biophysics; Membrane; Micelle; Lipid bilayer; Calcein; Membrane fluidity; Drug delivery; Chromatography; Biochemistry; Organic chemistry; Phospholipid; Aqueous solution","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004094845,0.0003654384,0.0004805771,0.0001472745,0.0002645529,0.0005058956,0.0003102746,0.0003605454,0.001828068],"category_scores_gemma":[0.000886512,0.0003582182,0.0002470432,0.0002211061,0.0005440439,0.0007299324,0.0003217284,0.0008387516,0.0003458526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00056603,"about_ca_system_score_gemma":0.0003250606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001029438,"about_ca_topic_score_gemma":0.001154305,"domain_scores_codex":[0.9996697,0.00007010369,0.00004631875,0.00005406463,0.00006772803,0.00009216995],"domain_scores_gemma":[0.9993042,0.0003329584,0.0001505298,0.00006007566,0.00006244295,0.00008979907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002513272,0.00009483111,0.0002475135,0.00006344191,0.00001755047,0.00007924568,0.00006516472,0.0002437724,0.9950507,0.0001087826,0.00003796231,0.001477728],"study_design_scores_gemma":[0.00003856844,0.0001133205,0.0005133949,0.000002211598,0.0000081356,0.00002352225,0.000009496181,0.0006296042,0.9984984,0.00001149655,0.0001474762,0.000004373444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980052,0.0005091794,0.000714229,0.00005377111,0.00001470834,0.00002007971,0.0001107036,0.00002502695,0.0005470357],"genre_scores_gemma":[0.9984836,0.0002194839,0.0005518471,0.0000358946,0.000008055966,0.00001550077,0.00009903834,0.00003003961,0.0005566074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001828068,"threshold_uncertainty_score":0.006115496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002201274138952701,"score_gpt":0.2110626781780709,"score_spread":0.2088614040391182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}