{"id":"W2078950703","doi":"10.1128/mcb.22.12.4113-4123.2002","title":"Proteasomal Inhibition Enhances Glucocorticoid Receptor Transactivation and Alters Its Subnuclear Trafficking","year":2002,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":159,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council Canada; University of Pittsburgh","keywords":"Transactivation; Biology; Glucocorticoid receptor; Cell biology; Glucocorticoid; Transcription factor; Endocrinology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001405999,0.0001962356,0.0001710283,0.00005562972,0.000111961,0.00003122232,0.0000635423,0.0002400726,0.0000953699],"category_scores_gemma":[0.00003864822,0.000193647,0.00006407299,0.00007146985,0.0001182349,0.000008850128,0.00004045542,0.000116676,0.00001759246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008012826,"about_ca_system_score_gemma":0.00001263464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006558291,"about_ca_topic_score_gemma":0.000001974059,"domain_scores_codex":[0.9988127,0.0001531303,0.0001976631,0.0004855244,0.00007294625,0.0002780285],"domain_scores_gemma":[0.9996102,0.00000921382,0.00007728314,0.0001572935,0.00003652042,0.0001094224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005402455,0.00003954862,0.0001820987,0.00005177526,0.00003172419,0.000005473406,0.0001423959,0.000006322553,0.9905885,0.0003946087,0.00003127495,0.008472288],"study_design_scores_gemma":[0.0006374597,0.0005551214,0.00004557486,0.00001793481,0.0000169144,0.00002858203,0.00006231604,0.0003274129,0.9887283,0.00006613007,0.009265024,0.0002491607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862649,0.004927129,0.007420808,0.000283419,0.000080975,0.0004714136,0.00001507394,0.00002502391,0.0005112559],"genre_scores_gemma":[0.9982626,0.0005317529,0.0003974938,0.0003782103,0.00008538959,0.00004902959,0.000129783,0.00002669642,0.0001389994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01199774,"threshold_uncertainty_score":0.7896697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01109153888337618,"score_gpt":0.2093842792255488,"score_spread":0.1982927403421726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}