{"id":"W2078981916","doi":"10.1021/ja0394028","title":"Probing the Transition States of Four Glucoside Hydrolyses with <sup>13</sup>C Kinetic Isotope Effects Measured at Natural Abundance by NMR Spectroscopy","year":2004,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Analytical Chemistry and Chromatography","field":"Chemistry","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Kinetic isotope effect; Natural abundance; Abundance (ecology); Nuclear magnetic resonance spectroscopy; Kinetic energy; Isotope; Spectroscopy; Glucoside; Carbon-13; Transition state; Radiochemistry; Stereochemistry; Deuterium; Mass spectrometry; Organic chemistry; Nuclear physics; Catalysis; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001614973,0.000285956,0.0005470293,0.000008963436,0.0001677473,0.00003441934,0.0006020224,0.00008074904,0.00002702359],"category_scores_gemma":[0.00006076227,0.0001536172,0.0007946801,0.0004134324,0.001108483,0.00009234363,0.00006192845,0.0007846466,8.020469e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002779868,"about_ca_system_score_gemma":0.00007966835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005553052,"about_ca_topic_score_gemma":0.000001200481,"domain_scores_codex":[0.9981788,0.00003714234,0.0004756661,0.0002292252,0.0007033672,0.000375755],"domain_scores_gemma":[0.9983885,0.0002356424,0.0007916728,0.0003133892,0.0001376914,0.0001330872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00029944,0.00014287,0.0006598219,0.0002032879,0.0004089821,0.000005369534,0.0007283739,0.002061203,0.994237,0.000002188215,0.00119923,0.00005220357],"study_design_scores_gemma":[0.001155729,0.0001060229,0.0001164875,0.0003734917,0.000314271,0.0001737596,0.0005947984,0.0008160213,0.995661,0.0003621678,0.0001253545,0.0002008605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966436,0.0006842018,0.000450948,0.001980867,0.00001244838,0.00008250325,0.00001368103,0.00002157638,0.0001101701],"genre_scores_gemma":[0.9979187,0.0001387607,0.001128291,0.0005817579,0.0001583749,0.000006075686,0.000005458176,0.00002954286,0.00003304573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001424006,"threshold_uncertainty_score":0.6264328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004133377704911475,"score_gpt":0.2067054825757145,"score_spread":0.202572104870803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}