{"id":"W2078982205","doi":"10.1016/j.jmb.2005.11.012","title":"Saccharomyces cerevisiae Ste50 Binds the MAPKKK Ste11 Through a Head-to-tail SAM Domain Interaction","year":2005,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; University of New Brunswick; University of Toronto; York University","funders":"University of Texas at San Antonio","keywords":"Saccharomyces cerevisiae; Mutant; Signal transduction; Protein kinase A; Cell biology; Biology; Amino acid; Biochemistry; Kinase; Yeast; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001554521,0.0003899201,0.0002691102,0.0001616731,0.0003437225,0.0004396155,0.0003111627,0.0003140374,0.004097502],"category_scores_gemma":[0.0002404651,0.000296935,0.0003871222,0.00008906003,0.0001832042,0.0002937845,0.0007193931,0.0004282127,0.003100233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004027339,"about_ca_system_score_gemma":0.0001677234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005026312,"about_ca_topic_score_gemma":0.001158568,"domain_scores_codex":[0.9998661,0.00002043056,0.00000840293,0.00002932021,0.00003202237,0.00004372892],"domain_scores_gemma":[0.9998775,0.00002873436,0.00002035539,0.00001702159,0.00001798664,0.00003844649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003752943,0.00005099769,0.001173271,0.00008367741,0.00002923863,0.0002021064,0.00003083759,0.0001398624,0.9938807,0.0003064607,0.0005663571,0.003161056],"study_design_scores_gemma":[0.00004215584,0.0001430374,0.0236935,0.00002431843,0.00003226734,0.0006934179,0.0001395185,0.003867275,0.9627702,0.0002391739,0.008332831,0.00002231511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896891,0.001387952,0.002958156,0.0001866864,0.00006182463,0.00001609389,0.0002283432,0.0002254584,0.005246367],"genre_scores_gemma":[0.9926516,0.000345553,0.001075598,0.00009300841,0.000009959394,0.00001084103,0.0005216737,0.00002521298,0.005266576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004097502,"threshold_uncertainty_score":0.01370746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01949642069616759,"score_gpt":0.3469090525836139,"score_spread":0.3274126318874463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}