{"id":"W2079053455","doi":"10.1186/1471-2229-10-252","title":"Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures","year":2010,"lang":"en","type":"article","venue":"BMC Plant Biology","topic":"Berberine and alkaloids research","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Plant Biotechnology Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Sanguinarine; Papaver; Biology; Opium Poppy; Proteome; Elicitor; Expressed sequence tag; Transcriptome; Thebaine; Secondary metabolism; Poppy; cDNA library; Complementary DNA; Biochemistry; Alkaloid; Botany; Biosynthesis; Gene expression; Gene; Codeine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003540516,0.00009888188,0.0003792666,0.0001940919,0.00002101765,0.000003675389,0.0001121158,0.0001223381,0.00003828519],"category_scores_gemma":[0.0001020504,0.0000518223,0.00005598777,0.0002083169,0.0001938097,0.00002952291,0.00002797074,0.00027917,0.000001563315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000365982,"about_ca_system_score_gemma":0.0000253336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006569945,"about_ca_topic_score_gemma":0.0009846924,"domain_scores_codex":[0.9991291,0.0001518982,0.0003039078,0.0001547073,0.00009830463,0.0001620805],"domain_scores_gemma":[0.9995129,0.0001191291,0.00008921089,0.0001658961,0.00006627855,0.0000465919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002302934,0.00009462213,0.02267171,0.0001013458,0.0000226042,0.000002052322,0.0003029795,4.964831e-7,0.9757001,0.0004488509,0.0000494692,0.0003754175],"study_design_scores_gemma":[0.001215581,0.0001978597,0.3770986,0.00003880437,0.00005216883,0.00004963207,0.0002048307,0.0001879,0.6191259,0.0003356237,0.001417603,0.00007544045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978936,0.000777742,0.0001064371,0.0002449374,0.00006247983,0.0004340598,0.0000803506,0.000005850056,0.000394578],"genre_scores_gemma":[0.9981388,0.0001882071,0.001238585,0.00005321108,0.00005338192,0.00002309147,0.0001632005,0.000005285663,0.0001362012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3565743,"threshold_uncertainty_score":0.2113252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05995045960992028,"score_gpt":0.3548268095723443,"score_spread":0.294876349962424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}