{"id":"W2079080908","doi":"10.1196/annals.1338.036","title":"Attenuation of UV‐Induced Apoptosis by Coenzyme Q<sub>10</sub> in Human Cells Harboring Large‐Scale Deletion of Mitochondrial DNA","year":2005,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"National Science Council","keywords":"Mitochondrial DNA; Coenzyme Q10; Mitochondrion; Apoptosis; Molecular biology; Biology; DNA fragmentation; Coenzyme Q – cytochrome c reductase; Programmed cell death; DNA damage; Cytochrome c; Fragmentation (computing); Apoptosis-inducing factor; Reactive oxygen species; DNA; Cell biology; Genetics; Caspase; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002303733,0.000384975,0.0004101101,0.0001367084,0.0001207727,0.0002131516,0.000223547,0.000322625,0.001065516],"category_scores_gemma":[0.0001805613,0.0001256891,0.0002328748,0.0001277732,0.0002143457,0.0001769988,0.0001847451,0.0003771948,0.0003131498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002298937,"about_ca_system_score_gemma":0.0001999158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001057102,"about_ca_topic_score_gemma":0.0009491126,"domain_scores_codex":[0.9999048,0.00002463103,0.00001498885,0.00002010303,0.00001883982,0.00001659783],"domain_scores_gemma":[0.999904,0.00003391871,0.0000207691,0.00001484997,0.00001368863,0.00001277991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002872541,0.00004700856,0.0001625241,0.00004885614,0.000007874911,0.00007499985,0.00002378784,0.00008328688,0.9978466,0.00005167969,0.00002504329,0.001341075],"study_design_scores_gemma":[0.00007960755,0.001252844,0.002705031,0.000008032022,0.00002507571,0.0003596311,0.00002155874,0.0007493312,0.9930176,0.00002879435,0.001748802,0.000003838764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945903,0.001613773,0.002664969,0.00007077994,0.00002541004,0.00006039286,0.0002035142,0.0000628757,0.0007080189],"genre_scores_gemma":[0.9950491,0.001068289,0.002020348,0.00004039292,0.000007889119,0.00006173221,0.0004646096,0.00001575598,0.001271788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001065516,"threshold_uncertainty_score":0.003564537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04149008587638572,"score_gpt":0.3029256005005936,"score_spread":0.2614355146242079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}