{"id":"W2079086346","doi":"10.1016/j.ijpddr.2014.05.002","title":"Quantitative proteomic analysis of amphotericin B resistance in Leishmania infantum","year":2014,"lang":"en","type":"article","venue":"International Journal for Parasitology Drugs and Drug Resistance","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Ministère du Développement Économique, de l’Innovation et de l’Exportation","keywords":"Stable isotope labeling by amino acids in cell culture; Leishmania infantum; Proteome; Biology; Mutant; Proteomics; Quantitative proteomics; Leishmania; Biochemistry; Cell biology; Microbiology; Leishmaniasis; Gene; Genetics; Visceral leishmaniasis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001427602,0.0002454949,0.0002136364,0.0003969294,0.0001472949,0.0002300296,0.000139223,0.0002300968,0.000452472],"category_scores_gemma":[0.0001461051,0.0001043187,0.0001887422,0.000320968,0.0001233313,0.0001950534,0.0001657454,0.0002378683,0.0001633133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001073929,"about_ca_system_score_gemma":0.00008231618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002602125,"about_ca_topic_score_gemma":0.0002961965,"domain_scores_codex":[0.9999171,0.00001292455,0.000006733485,0.00002438143,0.00002674925,0.0000121352],"domain_scores_gemma":[0.9999195,0.00001777747,0.00002460097,0.000006416188,0.00002025885,0.00001141002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003245714,0.000007025235,0.0002803206,0.00002220469,0.000003682794,0.00002410119,0.000009691432,0.00001227608,0.99905,0.000009605445,0.000007219954,0.0005413766],"study_design_scores_gemma":[0.000009422271,0.000373957,0.08709885,0.00001381962,0.00006554502,0.001471116,0.0002423616,0.001983305,0.906576,0.00009590071,0.002052758,0.00001710128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957496,0.0009258054,0.002211894,0.0000357773,0.000008361601,0.00001601103,0.0006114244,0.00003006124,0.0004110382],"genre_scores_gemma":[0.9878429,0.001424656,0.007419059,0.00006412616,0.00001173541,0.00004602455,0.001846686,0.00002427114,0.001320593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000452472,"threshold_uncertainty_score":0.0015136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01673406940489549,"score_gpt":0.3667464698279008,"score_spread":0.3500124004230053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}