{"id":"W2079163439","doi":"10.1016/j.jmb.2004.02.051","title":"Human Immunodeficiency Virus Type 1-neutralizing Monoclonal Antibody 2F5 is Multispecific for Sequences Flanking the DKW Core Epitope","year":2004,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Paratope; Epitope; Monoclonal antibody; Antibody; Molecular biology; Gp41; Chemistry; Peptide; Linear epitope; Virology; clone (Java method); Biology; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003749634,0.0007661183,0.0005170107,0.0005558886,0.00036999,0.0005253041,0.0006936904,0.0006557842,0.003405442],"category_scores_gemma":[0.0002635105,0.0004122226,0.0004195129,0.0002394945,0.0002957901,0.0003440303,0.0005032264,0.001139939,0.001029504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007781943,"about_ca_system_score_gemma":0.000347276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001097466,"about_ca_topic_score_gemma":0.002128012,"domain_scores_codex":[0.999582,0.00006309889,0.00002781123,0.00008340913,0.00008532868,0.0001584683],"domain_scores_gemma":[0.9997647,0.00005704641,0.00004139278,0.00002822667,0.00002451043,0.00008409328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001768826,0.0000660541,0.0005167964,0.00005256272,0.00001924067,0.0001105069,0.00001905289,0.00009573236,0.9954233,0.0004077544,0.0003473914,0.002764781],"study_design_scores_gemma":[0.0001467785,0.0008485112,0.01403068,0.00003761827,0.00007735761,0.00186461,0.00005433649,0.002567891,0.966444,0.0002245511,0.01368481,0.00001896703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841354,0.001884257,0.006097964,0.0002074898,0.0001545489,0.00008598019,0.0003138778,0.0001785715,0.006941897],"genre_scores_gemma":[0.9890181,0.0007395103,0.004790462,0.0002592652,0.00004795663,0.00004922145,0.001145604,0.00002577499,0.003924135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003405442,"threshold_uncertainty_score":0.01139235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04525715173935766,"score_gpt":0.3714695182537458,"score_spread":0.3262123665143881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}