{"id":"W2079172245","doi":"10.1002/jcb.10517","title":"hMad4, c‐Myc endogenous inhibitor, induces a replicative senescence‐like state when overexpressed in human fibroblasts","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institute on Aging","keywords":"Biology; Transactivation; Molecular biology; Cell growth; Cell culture; Northern blot; clone (Java method); Senescence; Complementary DNA; Cell biology; Gene expression; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001177683,0.0002531677,0.0001610487,0.0001986068,0.0001756953,0.0002112916,0.0001071335,0.0001151836,0.001034529],"category_scores_gemma":[0.0001036872,0.0001359681,0.0001548404,0.000122444,0.0001390204,0.00007667481,0.0001178265,0.0002711538,0.0003344772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002650197,"about_ca_system_score_gemma":0.0001807875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005774566,"about_ca_topic_score_gemma":0.0008343541,"domain_scores_codex":[0.9999419,0.000009765373,0.000005911813,0.00001122673,0.00001444925,0.00001664755],"domain_scores_gemma":[0.9999297,0.00001843675,0.00001330724,0.00001149338,0.000005917122,0.00002102998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007555015,0.00001053433,0.0001326451,0.00001383638,0.000003133698,0.00004594207,0.000006479509,0.00002503534,0.9991462,0.00004607449,0.00003003736,0.0004646162],"study_design_scores_gemma":[0.00001789272,0.0002094027,0.002576389,0.000002515403,0.000009790928,0.0002663777,0.00001323456,0.000450901,0.9942625,0.00003173438,0.00215736,0.00000187614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952008,0.001379214,0.001481622,0.00005036144,0.00002503876,0.000020387,0.0005016929,0.00009533964,0.001245723],"genre_scores_gemma":[0.9915479,0.0007977327,0.002092215,0.00003397476,0.00001409755,0.00003081618,0.00143409,0.00001626012,0.004032943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001034529,"threshold_uncertainty_score":0.003460824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095197985270245,"score_gpt":0.2494792147636777,"score_spread":0.2285272349109752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}