{"id":"W2079178949","doi":"10.1016/j.clinbiochem.2006.03.004","title":"Toxicology: Then and now","year":2006,"lang":"en","type":"review","venue":"Clinical Biochemistry","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Clinical toxicology; Forensic toxicology; Toxicology; Environmental toxicology; Pharmacology; Medicine; Biology; Chemistry; Toxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.001595692,0.0007152641,0.002290577,0.00007567283,0.0001785707,0.00003853273,0.0007075138,0.003052181,0.0007141746],"category_scores_gemma":[0.0003219772,0.0006015805,0.0008454025,0.0002028668,0.0008897175,0.00002518665,0.0004868381,0.002946401,0.0004714675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004779485,"about_ca_system_score_gemma":0.0004349157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001548307,"about_ca_topic_score_gemma":7.031774e-7,"domain_scores_codex":[0.9957012,0.0007916947,0.001598121,0.001091936,0.000156246,0.0006607972],"domain_scores_gemma":[0.9962708,0.001819898,0.0006392408,0.0005685067,0.00007452034,0.0006270289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002081372,0.0003712285,0.0001038629,0.003792626,0.0004208883,0.0000649038,0.000004627797,2.535648e-7,0.0001026691,0.00003626876,0.04904494,0.9460369],"study_design_scores_gemma":[0.0007897018,0.0000380758,0.00001111356,0.0004082206,0.00251272,0.00007943556,0.000002711298,0.00001310937,0.000460783,0.0001652261,0.994898,0.0006209091],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008871198,0.9817731,0.000003591935,0.0001407449,0.002298463,0.0005172691,0.0004558491,0.0001075069,0.01381631],"genre_scores_gemma":[0.00009884866,0.9883648,0.0001444128,0.001162397,0.002908259,0.0001106868,0.0003278886,0.00008259404,0.00680009],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9458531,"threshold_uncertainty_score":0.9996436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3213879074882492,"score_gpt":0.5782470575847082,"score_spread":0.256859150096459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}