{"id":"W2079182949","doi":"10.1016/j.jconrel.2012.08.021","title":"Design and characterization of novel cell-penetrating peptides from pituitary adenylate cyclase-activating polypeptide","year":2012,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Internalization; Intracellular; Endocytosis; Chemistry; Cell biology; Transfection; Biochemistry; Pinocytosis; Cell; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002716419,0.0003822529,0.0002999047,0.0001431295,0.0001967861,0.0004596887,0.000279865,0.0003943365,0.0005583834],"category_scores_gemma":[0.0003061683,0.000230302,0.0003269054,0.0001767844,0.0002827734,0.0003444954,0.0002084132,0.00078201,0.0003060268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004210016,"about_ca_system_score_gemma":0.0003346526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004837644,"about_ca_topic_score_gemma":0.0005369316,"domain_scores_codex":[0.9998331,0.00002179875,0.00001871895,0.0000318299,0.00005330204,0.00004124661],"domain_scores_gemma":[0.9997725,0.00004922082,0.00007481482,0.00001489292,0.00003399744,0.00005453633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005965934,0.00001484131,0.00005019462,0.00003221817,0.000003414611,0.00008362616,0.00001987777,0.0002016674,0.9985851,0.0001061144,0.00002002479,0.0008232157],"study_design_scores_gemma":[0.00005352483,0.0004320135,0.001196767,0.000006360945,0.00002456266,0.000408409,0.00003782492,0.001334216,0.9925724,0.00005527063,0.003865526,0.00001323734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792089,0.001458919,0.01747785,0.0001789194,0.00006409491,0.0001651332,0.0003749594,0.00004918453,0.001021974],"genre_scores_gemma":[0.9747396,0.001389276,0.01888767,0.0001726982,0.00002843397,0.0001175045,0.001509766,0.00003360434,0.003121384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005583834,"threshold_uncertainty_score":0.003054619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01382128849697123,"score_gpt":0.2309185739682166,"score_spread":0.2170972854712453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}