{"id":"W2079193485","doi":"10.1073/pnas.1120685109","title":"Origin of metazoan cadherin diversity and the antiquity of the classical cadherin/β-catenin complex","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Marine Invertebrate Physiology and Ecology","field":"Earth and Planetary Sciences","cited_by":203,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Defense Science and Engineering Graduate; National Aeronautics and Space Administration; National Institute of General Medical Sciences; Canadian Institute for Advanced Research; U.S. Department of Defense","keywords":"Cadherin; Biology; Multicellular organism; Evolutionary biology; Most recent common ancestor; myr; Gene; Phylogenetics; Genome; Genetics; Cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0017541,0.0000735577,0.0002148413,0.00004024026,0.0004721668,0.000004229845,0.0008529636,0.00006982886,0.0001754825],"category_scores_gemma":[0.0002436411,0.00003289154,0.00007592071,0.0003733513,0.00392181,0.0002724557,0.000389298,0.0001635268,0.00000120698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003034194,"about_ca_system_score_gemma":0.0000208832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004822748,"about_ca_topic_score_gemma":0.00001402816,"domain_scores_codex":[0.9989606,0.00004041047,0.0002454828,0.0001243311,0.0004679816,0.0001611795],"domain_scores_gemma":[0.9991578,0.0002879075,0.0004134842,0.00001230694,0.00009665084,0.00003183755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00005788769,0.00002396278,0.9555954,0.00003857544,0.00002641626,1.420819e-9,0.0004186596,0.00005592333,0.008700464,0.03439021,0.0004393409,0.000253156],"study_design_scores_gemma":[0.000186729,0.0000315722,0.9655083,0.000007551536,0.00002176112,0.000004086703,0.0001437358,0.002366586,0.01287424,0.01862896,0.0001871145,0.00003931333],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915406,0.00009415861,1.581053e-7,0.003155997,0.00004720946,0.0001233194,0.00002207237,0.0000025415,0.005014012],"genre_scores_gemma":[0.999504,0.00003060483,0.0001193921,0.0002089148,0.0000392645,5.694092e-7,2.135455e-7,6.209712e-7,0.00009637388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01576126,"threshold_uncertainty_score":0.998789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07991796301377596,"score_gpt":0.2775311471942872,"score_spread":0.1976131841805113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}