{"id":"W2079216888","doi":"10.1111/j.0105-2896.2006.00352.x","title":"At the crossroads: diverse roles of early thymocyte transcriptional regulators","year":2006,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; Sunnybrook Health Science Centre","funders":"","keywords":"Biology; Thymocyte; Transcription factor; Transcriptional regulation; T-cell receptor; Gene; Recombinase; Lineage (genetic); MYB; T cell; Genetics; Regulation of gene expression; Cell biology; Cell fate determination; Recombination-activating gene; Cre recombinase; Transgene; Recombination","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004422978,0.000283395,0.0003935503,0.0003858178,0.0002766742,0.001488666,0.0004189512,0.0004075418,0.0009775776],"category_scores_gemma":[0.0003155328,0.0001449704,0.0001717062,0.0003122381,0.0004869681,0.0009922944,0.0006556235,0.000977925,0.0005166917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003549728,"about_ca_system_score_gemma":0.000185651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002066249,"about_ca_topic_score_gemma":0.0002687026,"domain_scores_codex":[0.9997012,0.00005724868,0.00001698669,0.00008503713,0.0000787258,0.00006071183],"domain_scores_gemma":[0.9997827,0.00006643418,0.00002846677,0.00002072802,0.00003800121,0.00006360661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006292558,0.00003990636,0.003662838,0.0004986854,0.00003551471,0.0007411389,0.0004238535,0.0007492919,0.8572465,0.01622851,0.0006910199,0.1190534],"study_design_scores_gemma":[0.0001463394,0.001496092,0.08477858,0.000834903,0.0003064264,0.008532276,0.00202228,0.00826912,0.5438796,0.07480267,0.2747447,0.0001871086],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5742503,0.3568653,0.04058559,0.003167198,0.0003985847,0.00002936112,0.0003612384,0.0006141755,0.02372826],"genre_scores_gemma":[0.9218196,0.05678901,0.01027123,0.001081858,0.0005112765,0.00002142345,0.000288641,0.00009919564,0.009117753],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001488666,"threshold_uncertainty_score":0.003270328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05891615550423104,"score_gpt":0.3013020038157799,"score_spread":0.2423858483115489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}