{"id":"W2079371864","doi":"10.1111/j.1471-4159.2004.02382.x","title":"4‐Aminopyridine‐induced epileptogenesis depends on activation of mitogen‐activated protein kinase ERK","year":2004,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Ministero dell’Istruzione, dell’Università e della Ricerca; Savoy Foundation","keywords":"MAPK/ERK pathway; Kinase; Protein kinase A; Hippocampal formation; 4-Aminopyridine; Chemistry; Tetrodotoxin; Mitogen-activated protein kinase; Neuroscience; Cell biology; Biology; Biophysics; Biochemistry; Potassium channel","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005738458,0.0003708127,0.0002166209,0.0000933906,0.00009261179,0.0001336008,0.00009909044,0.0001115959,0.0008030977],"category_scores_gemma":[0.00006581831,0.00009986535,0.0002548633,0.00009138492,0.0001129887,0.0001488731,0.0001427629,0.0002954868,0.0001815046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001570205,"about_ca_system_score_gemma":0.0001219928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004055827,"about_ca_topic_score_gemma":0.0009306303,"domain_scores_codex":[0.9999492,0.000006509346,0.000005697926,0.000008588708,0.00001426485,0.00001562424],"domain_scores_gemma":[0.9999577,0.00000543493,0.00001831742,0.000004035474,0.000006787672,0.000007740271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001002699,0.0000163376,0.0001228649,0.00005046954,0.000004685185,0.00006805696,0.000007201748,0.00002994022,0.9988808,0.00002705784,0.00001344599,0.0006789988],"study_design_scores_gemma":[0.00002375563,0.0004294451,0.02345152,0.000007119848,0.00002040539,0.0004800328,0.00002385818,0.0006509604,0.9739057,0.00005472073,0.000947313,0.00000503106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953181,0.001756073,0.001327109,0.00004783874,0.00002323251,0.00002025512,0.0002000816,0.00004848863,0.001258754],"genre_scores_gemma":[0.9959265,0.00170796,0.001030257,0.0000277804,0.00001034036,0.0000243771,0.0002882998,0.000006238398,0.0009782906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008030977,"threshold_uncertainty_score":0.00268656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05918721938407923,"score_gpt":0.329307973462414,"score_spread":0.2701207540783348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}