{"id":"W2079387502","doi":"10.1016/j.canlet.2006.11.016","title":"Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells","year":2007,"lang":"en","type":"article","venue":"Cancer Letters","topic":"Bioactive Compounds in Plants","field":"Agricultural and Biological Sciences","cited_by":237,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University; KGK Synergize (Canada)","funders":"Canadian Institutes of Health Research","keywords":"Nobiletin; Cell growth; Apoptosis; Cell cycle; Cell cycle checkpoint; Programmed cell death; Biology; Cell culture; Flavonoid; Cytotoxicity; Pharmacology; Flavones; Cell; Cancer research; In vitro; Biochemistry; Antioxidant; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001404521,0.0002924148,0.0003742352,0.0005403836,0.0002847239,0.0002846628,0.0001481991,0.0003248187,0.002558183],"category_scores_gemma":[0.0002594705,0.0002013362,0.000285099,0.0003440457,0.0001782091,0.0002244821,0.0001613012,0.0004412704,0.0004792803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004710607,"about_ca_system_score_gemma":0.0003337812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004020528,"about_ca_topic_score_gemma":0.005119057,"domain_scores_codex":[0.9998701,0.00003516447,0.00001203602,0.00002256879,0.00002178814,0.00003835699],"domain_scores_gemma":[0.9998784,0.0000419469,0.00001335119,0.00002306993,0.00001914488,0.00002402075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001604526,0.0001388087,0.0006901238,0.0001173011,0.00002175243,0.0002018873,0.0001003262,0.00008663554,0.9928374,0.0001277079,0.0004032338,0.003670212],"study_design_scores_gemma":[0.000371952,0.00230102,0.02133068,0.00001823884,0.00007120417,0.001250903,0.0001395729,0.0007517403,0.9633456,0.0001399177,0.01026704,0.00001218351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887624,0.005421764,0.000484458,0.0002020562,0.00007503671,0.00006030767,0.0006357891,0.00005779634,0.004300385],"genre_scores_gemma":[0.9913646,0.001924039,0.000457484,0.00007826155,0.00001685884,0.00005428303,0.00108348,0.00001328627,0.005007674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004020528,"threshold_uncertainty_score":0.008557916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01583934105234847,"score_gpt":0.2387455828146272,"score_spread":0.2229062417622787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}