{"id":"W2079388780","doi":"10.1038/nchembio.590","title":"Antibiotics as probes of biological complexity","year":2011,"lang":"en","type":"review","venue":"Nature Chemical Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Antibiotics; Biology; Biogenesis; Computational biology; Bacterial cell structure; Genetics; Bacteria; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001592467,0.001879593,0.001802329,0.002662078,0.0004198884,0.001431404,0.001560873,0.002848329,0.001964638],"category_scores_gemma":[0.001979831,0.0006426772,0.0004360188,0.003322673,0.002380522,0.003147278,0.00142178,0.00392024,0.001990128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00180213,"about_ca_system_score_gemma":0.001374672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001128285,"about_ca_topic_score_gemma":0.002497392,"domain_scores_codex":[0.9994794,0.0001015623,0.00005593635,0.00008158352,0.0002293698,0.00005223187],"domain_scores_gemma":[0.9990369,0.0005479968,0.00009629069,0.00004969143,0.0001936308,0.00007543959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001058868,0.00008420117,0.0001546198,0.008031028,0.00005592065,0.0001799414,0.00005803792,0.000595247,0.006860896,0.02536226,0.05436357,0.9041485],"study_design_scores_gemma":[0.00001931913,0.00003521008,0.0002074717,0.0008548393,0.00003948279,0.000427702,0.00003097681,0.0001312194,0.001880134,0.005858151,0.9904964,0.00001911657],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008619807,0.9959267,0.0009568876,0.0007030613,0.0008657477,0.000005621683,0.00001414047,0.00001390079,0.001427718],"genre_scores_gemma":[0.001113349,0.9948397,0.000804487,0.0007741418,0.0007090476,0.0000207264,0.00002861822,0.000004727926,0.001705135],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002848329,"threshold_uncertainty_score":0.01307541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05186617708019575,"score_gpt":0.332671986192589,"score_spread":0.2808058091123932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}