{"id":"W2079388780","doi":"10.1038/nchembio.590","title":"Antibiotics as probes of biological complexity","year":2011,"lang":"en","type":"review","venue":"Nature Chemical Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Antibiotics; Biology; Biogenesis; Computational biology; Bacterial cell structure; Genetics; Bacteria; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001675154,0.0005847961,0.001674785,0.0001068667,0.0000324445,0.000007309963,0.001044112,0.008367556,0.00009047493],"category_scores_gemma":[0.000356808,0.0004075669,0.0006099485,0.0002133563,0.001221452,9.416684e-7,0.000819664,0.001132532,0.00003710342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001765807,"about_ca_system_score_gemma":0.0001898944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007482075,"about_ca_topic_score_gemma":0.000002200667,"domain_scores_codex":[0.9976284,0.0001608557,0.0007208002,0.0009369766,0.00006227943,0.0004907014],"domain_scores_gemma":[0.9984577,0.00003929541,0.0004856528,0.0007614894,0.0001397127,0.0001161469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001185878,0.0003487878,0.00004295595,0.002399727,0.0005217174,0.000005252914,0.000004487671,4.847776e-9,0.4718543,0.01400793,0.0009224946,0.5097737],"study_design_scores_gemma":[0.000149861,0.000492968,0.000002285965,0.000285711,0.000124406,0.00008573008,0.000001343063,5.501498e-8,0.1917248,0.00116142,0.8055921,0.0003793256],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00660214,0.9909465,0.00001179047,0.00002562981,0.0004979857,0.0004866405,0.000375511,0.00003281483,0.001020956],"genre_scores_gemma":[0.01071758,0.9844675,0.001671488,0.0001097767,0.0005120991,0.000007073179,0.002415225,0.00004692965,0.0000522882],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8046696,"threshold_uncertainty_score":0.9998376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05186617708019575,"score_gpt":0.332671986192589,"score_spread":0.2808058091123932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}