{"id":"W2079479634","doi":"10.1016/j.peptides.2006.08.023","title":"A peptide inhibitor of MurA UDP-N-acetylglucosamine enolpyruvyl transferase: The first committed step in peptidoglycan biosynthesis","year":2006,"lang":"en","type":"article","venue":"Peptides","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Biopanning; Mura; Peptide; Biochemistry; Enzyme; Transferase; Phage display; Biology; Peptidomimetic; IC50; Chemistry; Molecular biology; Peptide library; Peptide sequence; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002391118,0.0002772765,0.0003205072,0.0001120788,0.0001012088,0.0000295712,0.0004447078,0.0003270855,0.00003719461],"category_scores_gemma":[0.00005564989,0.000213684,0.0001569514,0.0002861431,0.0003691321,0.000004469538,0.0001323772,0.0001690275,0.000007910247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002144825,"about_ca_system_score_gemma":0.00005263466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008881486,"about_ca_topic_score_gemma":0.007653762,"domain_scores_codex":[0.9984579,0.00006758426,0.0005085494,0.0004119891,0.0001544327,0.0003995315],"domain_scores_gemma":[0.9991263,0.00004492183,0.0001285252,0.0005791521,0.00007858982,0.00004250744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001468436,0.0001946599,0.006387623,0.00004211288,0.00003751441,0.000004474509,0.00004869844,0.00003252076,0.9874681,0.0001697958,0.002784244,0.002683366],"study_design_scores_gemma":[0.0008325936,0.0003686256,0.03036386,0.00005326415,0.00002746723,0.00001200149,0.0001730106,0.00005040192,0.8693043,0.00006655407,0.09845904,0.00028887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959754,0.0006941407,0.00008781382,0.001955518,0.0001415889,0.0003372634,0.00009844835,0.00002394024,0.0006858636],"genre_scores_gemma":[0.9979562,0.0002958608,0.0007627835,0.0001571098,0.0003456573,0.00004536071,0.0001055871,0.00003714564,0.0002942846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1181638,"threshold_uncertainty_score":0.8713779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005626837422635584,"score_gpt":0.1988620874460998,"score_spread":0.1932352500234642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}