{"id":"W2079479634","doi":"10.1016/j.peptides.2006.08.023","title":"A peptide inhibitor of MurA UDP-N-acetylglucosamine enolpyruvyl transferase: The first committed step in peptidoglycan biosynthesis","year":2006,"lang":"en","type":"article","venue":"Peptides","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Biopanning; Mura; Peptide; Biochemistry; Enzyme; Transferase; Phage display; Biology; Peptidomimetic; IC50; Chemistry; Molecular biology; Peptide library; Peptide sequence; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001908075,0.0005798698,0.0003851982,0.0002280355,0.0001543797,0.0003713515,0.0005068925,0.0003775119,0.001425104],"category_scores_gemma":[0.0001789496,0.000174907,0.0001908148,0.000139066,0.0001944882,0.0002199349,0.0001882255,0.0008302132,0.0005735059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003098451,"about_ca_system_score_gemma":0.0003001301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004330767,"about_ca_topic_score_gemma":0.0004204588,"domain_scores_codex":[0.9998916,0.00001580725,0.000009183762,0.00001860245,0.00003375762,0.00003101835],"domain_scores_gemma":[0.9999073,0.00001887008,0.00001855805,0.0000082498,0.0000113454,0.00003565602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008951872,0.0002834892,0.0001907701,0.0001228389,0.00003121295,0.0002510981,0.00001153335,0.0006761653,0.9832057,0.000871619,0.0004868309,0.01297346],"study_design_scores_gemma":[0.0001561822,0.0008167767,0.0004318709,0.000006527738,0.00002988367,0.0004584853,0.000003847977,0.001262164,0.9903134,0.00007251162,0.00644132,0.000007021491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9433221,0.01765469,0.0228659,0.0006279742,0.0006359234,0.0003497387,0.000936093,0.000708955,0.01289868],"genre_scores_gemma":[0.980494,0.005216432,0.005751649,0.0001881547,0.00009042385,0.00007550154,0.0007957387,0.00004018049,0.007347774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001425104,"threshold_uncertainty_score":0.004767478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005626837422635584,"score_gpt":0.1988620874460998,"score_spread":0.1932352500234642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}