{"id":"W2079513879","doi":"10.1182/blood-2010-06-292243","title":"Integrin β7-mediated regulation of multiple myeloma cell adhesion, migration, and invasion","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":162,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"National Cancer Institute; Terry Fox Foundation; Alberta Cancer Foundation; Multiple Myeloma Research Foundation; Georgia Cancer Coalition","keywords":"Integrin; Bortezomib; Homing (biology); Focal adhesion; Cell biology; Fibronectin; Cancer research; Cell adhesion; Cell adhesion molecule; Cell migration; Biology; Gene silencing; Transplantation; Cell; Chemistry; Immunology; Signal transduction; Multiple myeloma; Extracellular matrix; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001074777,0.0001076284,0.0001839865,0.0001310934,0.00004320383,0.000004976763,0.00004327797,0.00008487624,0.0001547106],"category_scores_gemma":[0.0003004224,0.00008196403,0.00004197755,0.0001458595,0.00005871559,0.00007973619,0.00003595851,0.00008432203,0.00003951669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001287351,"about_ca_system_score_gemma":0.0000444305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004882745,"about_ca_topic_score_gemma":0.0002198175,"domain_scores_codex":[0.9991425,0.00004630676,0.000231383,0.0001974901,0.0002245053,0.0001578527],"domain_scores_gemma":[0.9992856,0.00008763326,0.00008284902,0.0002231635,0.0001603777,0.0001603199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003221395,0.0009911032,0.7290863,0.0001022942,0.00005440146,0.00002394034,0.0006836428,6.381234e-8,0.2661625,0.00001710731,0.0001395256,0.002416999],"study_design_scores_gemma":[0.004008015,0.0003580172,0.5886853,0.00005404737,0.00005228183,0.00001241938,0.00007564645,0.0001559459,0.4064191,0.00004314061,0.00009174912,0.00004434506],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976616,0.0002919163,0.00003348029,0.00005706857,0.00002128518,0.0004042651,0.00001288741,0.00003473484,0.001482792],"genre_scores_gemma":[0.9961381,0.0001447229,0.003169609,0.00001925446,0.00002816698,0.00002074601,0.0001310979,0.00001412775,0.0003341728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.140401,"threshold_uncertainty_score":0.3342396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03439741748884629,"score_gpt":0.2509290326101518,"score_spread":0.2165316151213055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}