{"id":"W2079513879","doi":"10.1182/blood-2010-06-292243","title":"Integrin β7-mediated regulation of multiple myeloma cell adhesion, migration, and invasion","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":162,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"National Cancer Institute; Terry Fox Foundation; Alberta Cancer Foundation; Multiple Myeloma Research Foundation; Georgia Cancer Coalition","keywords":"Integrin; Bortezomib; Homing (biology); Focal adhesion; Cell biology; Fibronectin; Cancer research; Cell adhesion; Cell adhesion molecule; Cell migration; Biology; Gene silencing; Transplantation; Cell; Chemistry; Immunology; Signal transduction; Multiple myeloma; Extracellular matrix; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007778627,0.0002165944,0.0001513747,0.0002243231,0.0001555264,0.0002823464,0.0000990347,0.0001369696,0.0009356554],"category_scores_gemma":[0.00005219784,0.00008017863,0.0001751971,0.0001577555,0.000147689,0.00009661882,0.0001452882,0.0003515783,0.0002489447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003487582,"about_ca_system_score_gemma":0.0001861146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001252484,"about_ca_topic_score_gemma":0.001708754,"domain_scores_codex":[0.9998902,0.00001582801,0.000005370951,0.00001661764,0.00003005225,0.00004197521],"domain_scores_gemma":[0.9999748,0.000003142672,0.000006172747,0.000002447086,0.000006824221,0.000006521642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009251081,0.00002683303,0.000356397,0.00004465304,0.000007156495,0.00004380124,0.00001985992,0.00004882366,0.9950192,0.0003330492,0.0001434839,0.003864167],"study_design_scores_gemma":[0.00001812432,0.0002011897,0.01486874,0.00001080382,0.0000241843,0.0001617117,0.00007123858,0.001304445,0.9762434,0.0001273425,0.006964043,0.000004602156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831528,0.007039532,0.002896689,0.000176349,0.00004481104,0.00002568797,0.0002889553,0.0001099767,0.006265202],"genre_scores_gemma":[0.9918717,0.002806902,0.0009014972,0.0000690965,0.00001118851,0.00003676339,0.0004249618,0.00001410821,0.003863763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001252484,"threshold_uncertainty_score":0.003130019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03439741748884629,"score_gpt":0.2509290326101518,"score_spread":0.2165316151213055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}