{"id":"W2079547681","doi":"10.1016/j.reprotox.2012.10.012","title":"Selective induction of glutathione S-transferases in round spermatids from the Brown-Norway rat by the chemotherapeutic regimen for testicular cancer","year":2012,"lang":"en","type":"article","venue":"Reproductive Toxicology","topic":"Glutathione Transferases and Polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Children's Hospital; McGill University Health Centre; McGill University","funders":"","keywords":"Biology; Cisplatin; Isozyme; Etoposide; Glutathione; Epigenetics; DNA methylation; Bleomycin; DNA damage; Gene expression; Testicular cancer; Offspring; Molecular biology; Cancer research; Cancer; Andrology; Gene; Enzyme; DNA; Genetics; Biochemistry; Chemotherapy; Medicine; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000456762,0.0002106382,0.0002588808,0.00002883622,0.0001356032,0.00001048126,0.0002120975,0.0001910206,0.00004767716],"category_scores_gemma":[0.0001466355,0.0001378314,0.0001105015,0.0001955258,0.000303291,0.00001797644,0.00002794449,0.0001931247,0.000003057901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005776711,"about_ca_system_score_gemma":0.000100747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004988646,"about_ca_topic_score_gemma":0.0002529041,"domain_scores_codex":[0.9984788,0.0002756691,0.0002993897,0.0004577019,0.0001154056,0.0003730636],"domain_scores_gemma":[0.9990763,0.00017931,0.0001018526,0.0004722541,0.0001248315,0.00004545542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004306964,0.0002676932,0.004472149,0.00001347809,0.0001880009,1.87917e-7,0.00141096,0.00008818547,0.9882885,0.000222174,0.002122851,0.002495174],"study_design_scores_gemma":[0.001024478,0.0004516162,0.01869393,0.00001556278,0.0001136257,0.00002304509,0.0005106687,0.00001681981,0.9643698,0.0003481458,0.01423123,0.0002010608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800296,0.01137372,0.001441238,0.0055365,0.0004357491,0.000963308,0.0001508651,0.000007845609,0.00006116821],"genre_scores_gemma":[0.9972032,0.0004954219,0.0001651027,0.0007020563,0.0007512278,0.0003126886,0.00009077253,0.00003132125,0.0002481966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02391863,"threshold_uncertainty_score":0.5620599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01914349003500834,"score_gpt":0.277259376832068,"score_spread":0.2581158867970597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}