{"id":"W2079634662","doi":"10.1016/j.tiv.2007.08.003","title":"Modulation of TCDD-mediated induction of cytochrome P450 1A1 by mercury, lead, and copper in human HepG2 cell line","year":2007,"lang":"en","type":"article","venue":"Toxicology in Vitro","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Mercury (programming language); Cytochrome P450; Carcinogen; Environmental chemistry; Copper; Metal; Cell culture; Toxicity; Heavy metals; Biochemistry; Enzyme; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001644435,0.0002971344,0.000312908,0.0003140123,0.0002952984,0.0002309703,0.0001216349,0.0001598994,0.002131851],"category_scores_gemma":[0.0001409028,0.000170226,0.0003551946,0.0004237866,0.0002466523,0.0001341301,0.0001540662,0.0003432074,0.0004671808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003235188,"about_ca_system_score_gemma":0.000259942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003392651,"about_ca_topic_score_gemma":0.003998474,"domain_scores_codex":[0.9998114,0.00005615797,0.00002178687,0.00003063441,0.0000345424,0.00004555459],"domain_scores_gemma":[0.9999007,0.00003672459,0.00001005478,0.00001807748,0.0000199953,0.00001440635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005978703,0.00006373151,0.0007248744,0.00007989363,0.00001205066,0.00015114,0.00007456542,0.00006495294,0.9966925,0.00008310808,0.0001475531,0.001307824],"study_design_scores_gemma":[0.00002919427,0.0004384301,0.00750909,0.000005360097,0.00002322767,0.0001920872,0.00006932351,0.0003122772,0.989734,0.00003451538,0.001646188,0.000006434399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929392,0.001897889,0.001601704,0.0001436888,0.00006289453,0.00003190037,0.001119273,0.00008723784,0.002116155],"genre_scores_gemma":[0.9895211,0.00127043,0.001336496,0.00005698545,0.00002435322,0.00005231274,0.002333677,0.00001629699,0.005388351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003392651,"threshold_uncertainty_score":0.007131755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.010679676973928,"score_gpt":0.2579883279862137,"score_spread":0.2473086510122857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}