{"id":"W2079647238","doi":"10.1038/nrc2545","title":"Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer","year":2008,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":411,"is_retracted":false,"has_abstract":false,"ca_institutions":"Jennerex Biotherapeutics (Canada)","funders":"","keywords":"Oncolytic virus; Cancer; Cancer therapy; Medicine; Cancer research; Computational biology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000836698,0.001222133,0.001495096,0.001511097,0.0003012145,0.00115225,0.001529603,0.001695781,0.002856322],"category_scores_gemma":[0.0004225018,0.0003871972,0.0004339979,0.001418349,0.0008770637,0.001838723,0.000793486,0.003296583,0.002782451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008862836,"about_ca_system_score_gemma":0.0006573754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004922419,"about_ca_topic_score_gemma":0.0008903718,"domain_scores_codex":[0.9998156,0.00002703104,0.00001385902,0.00003121731,0.00008882778,0.00002356217],"domain_scores_gemma":[0.9998264,0.0000750272,0.00001960873,0.000009617265,0.00004500007,0.00002425434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001330584,0.0001247537,0.0001031247,0.004555479,0.00006725697,0.0003549877,0.00006483349,0.0006379539,0.0167403,0.01444214,0.04597024,0.9168058],"study_design_scores_gemma":[0.00004580438,0.00011341,0.0002064245,0.0005381034,0.00004015082,0.001507181,0.00002907776,0.0001566037,0.003478697,0.003042913,0.9908231,0.00001850288],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003856366,0.9937007,0.001938902,0.000637927,0.0006908166,0.00001608259,0.0000287968,0.0000449174,0.002556159],"genre_scores_gemma":[0.001797267,0.9944148,0.0009954583,0.0003551663,0.0001860304,0.00002480369,0.00005419718,0.000004953336,0.002167311],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002856322,"threshold_uncertainty_score":0.00955534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09518882470295026,"score_gpt":0.4407952146786674,"score_spread":0.3456063899757171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}