{"id":"W2079671323","doi":"10.1016/j.chom.2013.08.015","title":"The Interferon-Inducible MxB Protein Inhibits HIV-1 Infection","year":2013,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":327,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Cypa; Biology; Cyclophilin A; Virology; Capsid; Interferon; SAMHD1; Infectivity; Antiviral protein; Virus; Peptidylprolyl isomerase; Viral replication; Cyclophilin; Molecular biology; RNA; Genetics; Gene; Reverse transcriptase; Isomerase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001701143,0.0001875771,0.0001533347,0.00007061805,0.0004867672,0.00008700288,0.0002020242,0.0001736898,0.001633944],"category_scores_gemma":[0.00003180262,0.0001220462,0.00008905373,0.0001294718,0.0002113222,0.000124425,0.0001711398,0.0003872204,0.05814171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009119543,"about_ca_system_score_gemma":0.00007390976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007461667,"about_ca_topic_score_gemma":0.0001151538,"domain_scores_codex":[0.998696,0.0001798915,0.0002157381,0.0003038326,0.00003228589,0.0005722077],"domain_scores_gemma":[0.9993158,0.00007206303,0.00007026151,0.0003966128,0.00009886578,0.00004640344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004114792,0.0001754541,0.001167689,0.00001466146,0.00006106538,0.000002339481,0.000182386,2.602557e-7,0.9381226,0.00004038234,0.05488027,0.005311785],"study_design_scores_gemma":[0.0007864749,0.0002721455,0.002292499,0.00002582312,0.000009003145,0.00001832268,0.00007191583,4.600825e-7,0.7660586,0.00003696058,0.2303162,0.0001116482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860073,0.002755899,0.00005970401,0.0009641393,0.0003102549,0.001046585,0.00002678244,0.00008053715,0.008748794],"genre_scores_gemma":[0.939861,0.0001532475,0.00003008017,0.00006728056,0.00003483445,0.0002878033,0.0001415043,0.00002074312,0.05940353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1754359,"threshold_uncertainty_score":0.9992787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0087956312849027,"score_gpt":0.2214547456638154,"score_spread":0.2126591143789127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}