{"id":"W2079671323","doi":"10.1016/j.chom.2013.08.015","title":"The Interferon-Inducible MxB Protein Inhibits HIV-1 Infection","year":2013,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":327,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Cypa; Biology; Cyclophilin A; Virology; Capsid; Interferon; SAMHD1; Infectivity; Antiviral protein; Virus; Peptidylprolyl isomerase; Viral replication; Cyclophilin; Molecular biology; RNA; Genetics; Gene; Reverse transcriptase; Isomerase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002341064,0.0003243638,0.0003118103,0.0002835639,0.0003042,0.0004709593,0.0002306597,0.0003137172,0.001537129],"category_scores_gemma":[0.0002088656,0.000157043,0.0002781161,0.0001110856,0.0002826061,0.0001799422,0.0001893657,0.001171763,0.0004550369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003180414,"about_ca_system_score_gemma":0.0003619758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004245371,"about_ca_topic_score_gemma":0.0008998853,"domain_scores_codex":[0.9998629,0.00003098293,0.000006396006,0.0000102179,0.0000334506,0.00005588912],"domain_scores_gemma":[0.999934,0.00001710409,0.00001020459,0.00001028133,0.000005207442,0.00002321193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001479015,0.0007407249,0.0005233064,0.00009037919,0.00002674941,0.00005270087,0.0000401914,0.0007048526,0.9731225,0.000855606,0.001216757,0.02114713],"study_design_scores_gemma":[0.0006637178,0.004709376,0.01085946,0.00003749546,0.00006034618,0.0003503686,0.00007160453,0.004093673,0.9659236,0.0004974284,0.01271531,0.00001767414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867615,0.004677375,0.001406812,0.0004695189,0.0002228647,0.00005254762,0.000240254,0.0002118853,0.005957155],"genre_scores_gemma":[0.9936314,0.001596687,0.0007224552,0.00007211861,0.00005390324,0.00003222103,0.0003241569,0.00001835759,0.003548699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001537129,"threshold_uncertainty_score":0.005142272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0087956312849027,"score_gpt":0.2214547456638154,"score_spread":0.2126591143789127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}