{"id":"W2079693436","doi":"10.1139/cjc-2012-0429","title":"Structural characterization of the model amphipathic peptide Ac-LKKLLKLLKKLLKL-NH<sub>2</sub> in aqueous solution and with 2,2,2-trifluoroethanol and 1,1,1,3,3,3-hexafluoroisopropanol","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Peptide; Amphiphile; Tetramer; Aqueous solution; Circular dichroism; Peptide Conformation; Monomer; Crystallography; Stereochemistry; Protein secondary structure; Organic chemistry; Biochemistry; Copolymer; Enzyme","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001646734,0.0002362946,0.0001342973,0.00007569457,0.0001314894,0.0001406524,0.0001328828,0.0002616614,0.0004495931],"category_scores_gemma":[0.0002576689,0.0001042215,0.0001269387,0.0001245346,0.000197249,0.0001972843,0.00008424447,0.0002848271,0.000174526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001402202,"about_ca_system_score_gemma":0.0001407703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005591566,"about_ca_topic_score_gemma":0.0004861861,"domain_scores_codex":[0.9999239,0.00001655297,0.000004786807,0.00001311084,0.00002379364,0.00001772456],"domain_scores_gemma":[0.9998434,0.00004664853,0.00004590893,0.000006487352,0.00002783219,0.00002971726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002872304,0.000006392197,0.00005964855,0.000009853012,0.000001226891,0.00001087483,0.000007128774,0.00006607777,0.9996277,0.000006555051,0.000003817039,0.0001720814],"study_design_scores_gemma":[0.000006192902,0.0002006199,0.002449526,0.000003081235,0.000007633465,0.0000741169,0.00001891143,0.0008786395,0.9959093,0.00001322963,0.0004347452,0.000003997599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981804,0.0002892189,0.001106037,0.00002950468,0.000003433253,0.00001151216,0.00008523212,0.000009008965,0.0002856957],"genre_scores_gemma":[0.9952828,0.0004298262,0.00276968,0.00006450742,0.000005585711,0.00002549777,0.0005797838,0.00001363507,0.000828648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005591566,"threshold_uncertainty_score":0.001504064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005757949791859043,"score_gpt":0.1629617547926613,"score_spread":0.1572038050008022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}