{"id":"W2079694321","doi":"10.1128/mcb.25.14.6247-6258.2005","title":"Gamma Interferon-Inducible Protein 10 Induces HeLa Cell Apoptosis through a p53-Dependent Pathway Initiated by Suppression of Human Papillomavirus Type 18 E6 and E7 Expression","year":2005,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of British Columbia and Yukon; Cleveland Clinic; Cleveland Clinic Foundation; Heart and Stroke Foundation of Canada","keywords":"Biology; Apoptosis; Transfection; HeLa; Signal transduction; Interferon; Molecular biology; Chemokine; Viral replication; Oncogene; Cell culture; Cell biology; Cell cycle; Cancer research; Virology; Immunology; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002331282,0.0003409394,0.0004966799,0.0001264772,0.0001936426,0.00002091373,0.0002361453,0.0006418324,0.001018933],"category_scores_gemma":[0.00003483827,0.0002784357,0.00008769349,0.00009520378,0.000375504,0.00009747454,0.0003230827,0.0003716722,0.00006902105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002180312,"about_ca_system_score_gemma":0.00003943168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001151915,"about_ca_topic_score_gemma":0.000003369974,"domain_scores_codex":[0.9977305,0.0007399174,0.0004812128,0.0005606188,0.0000476841,0.0004400771],"domain_scores_gemma":[0.9992413,0.00004659208,0.0002119208,0.0003680684,0.00008780997,0.00004431173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008050791,0.000266024,0.00005025671,0.00004828411,0.00008190326,0.000005965271,0.0004749025,2.65851e-7,0.995653,0.0001534909,0.0006916388,0.001769149],"study_design_scores_gemma":[0.001692258,0.00202687,0.00001533521,0.0001185277,0.0000351664,0.00002158744,0.0002890523,0.000001216045,0.9826038,0.0001172226,0.01277585,0.0003030673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9785948,0.01895147,0.0002832992,0.00007166577,0.0001693058,0.0003758057,0.00004826824,0.00004425781,0.001461113],"genre_scores_gemma":[0.9963499,0.0002275139,0.00008794976,0.0001182251,0.00001709185,0.00003757076,0.0003532909,0.00003376151,0.002774663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01872396,"threshold_uncertainty_score":0.9999668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02112081770853122,"score_gpt":0.2625516229684632,"score_spread":0.241430805259932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}