{"id":"W2079700993","doi":"10.1210/jc.2007-0359","title":"The Uridine Diphosphate Glucuronosyltransferase 2B15 D85Y and 2B17 Deletion Polymorphisms Predict the Glucuronidation Pattern of Androgens and Fat Mass in Men","year":2007,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"Glucuronidation; Androsterone; Endocrinology; Glucuronosyltransferase; Internal medicine; Chemistry; Dihydrotestosterone; Androgen; Glucuronide; Uridine diphosphate; Urine; Hormone; Biology; Medicine; Steroid; Biochemistry; Microsome; In vitro; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009358855,0.0002916626,0.00078243,0.0001390957,0.0003567461,0.00002220701,0.0006374705,0.0002665648,0.00006042681],"category_scores_gemma":[0.0004578663,0.0001527251,0.0002092005,0.0002078328,0.001369354,0.0001343432,0.0001459577,0.001866604,0.000003970984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001399216,"about_ca_system_score_gemma":0.00009304759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006459023,"about_ca_topic_score_gemma":0.00005127387,"domain_scores_codex":[0.9942466,0.002437924,0.002061398,0.0002468698,0.0003485706,0.0006586415],"domain_scores_gemma":[0.9937055,0.004536958,0.0009677106,0.0003036566,0.0002193832,0.0002668244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.008982143,0.0007445624,0.1193534,0.0000466523,0.001708621,0.0001802155,0.002477992,0.0006856382,0.1113092,0.004502427,0.0010557,0.7489535],"study_design_scores_gemma":[0.01910476,0.000742855,0.5352752,0.00004431705,0.003115581,0.0008184473,0.000872676,0.003230134,0.1938064,0.005523252,0.2369902,0.000476225],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.943285,0.04506911,0.00119833,0.008055946,0.001713049,0.0004405881,0.00003096623,0.0000104037,0.0001966423],"genre_scores_gemma":[0.9088297,0.08873335,0.00005527745,0.001476107,0.000827468,0.000006969341,0.000002717348,0.00002214545,0.00004623047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7484772,"threshold_uncertainty_score":0.810957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07418747677206014,"score_gpt":0.4267331738783499,"score_spread":0.3525456971062897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}