{"id":"W2079824715","doi":"10.1007/s10911-010-9163-3","title":"Gene Expression in the Third Dimension: The ECM-nucleus Connection","year":2010,"lang":"en","type":"review","venue":"Journal of Mammary Gland Biology and Neoplasia","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Extracellular matrix; Biology; Cell biology; Morphogenesis; Context (archaeology); Nuclear matrix; Function (biology); Phenotype; Gene expression; Extracellular; Regulation of gene expression; Matrix (chemical analysis); Nucleus; Gene; Scaffold/matrix attachment region; Genetics; Chromatin; Chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001010548,0.001076531,0.002215386,0.001356684,0.0003872313,0.002078297,0.001533722,0.002800938,0.001997578],"category_scores_gemma":[0.0005895866,0.0004537585,0.0004249008,0.001858594,0.002189801,0.0030229,0.001277457,0.002942853,0.001887481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00128851,"about_ca_system_score_gemma":0.001228675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008453377,"about_ca_topic_score_gemma":0.001524815,"domain_scores_codex":[0.9997355,0.00005058137,0.0000335988,0.0000668433,0.00007921223,0.00003416363],"domain_scores_gemma":[0.9995949,0.0001883213,0.00004290389,0.00002216677,0.0001073207,0.00004442228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002082236,0.00006624844,0.0004747326,0.009147089,0.0001239616,0.0009381705,0.0001694451,0.0009641444,0.01811266,0.04171046,0.04312178,0.8849632],"study_design_scores_gemma":[0.0000269449,0.00006996725,0.000928102,0.00139133,0.00007431011,0.001871921,0.0001832856,0.0002556809,0.002568225,0.01516907,0.9774209,0.00004025859],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002089552,0.99676,0.0006732249,0.0008725452,0.0005210019,0.000002400779,0.00001575376,0.0000106704,0.0009355171],"genre_scores_gemma":[0.001564631,0.995966,0.0004729872,0.0004957267,0.0005282129,0.000006197177,0.0000224688,0.000002662172,0.0009411408],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002800938,"threshold_uncertainty_score":0.00934881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0175273980196071,"score_gpt":0.3037817762090697,"score_spread":0.2862543781894625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}