{"id":"W2079827686","doi":"10.1021/bi051593z","title":"Binding of Protein Phosphatase 2A to the L-Type Calcium Channel Ca <sub>v</sub> 1.2 next to Ser1928, Its Main PKA Site, Is Critical for Ser1928 Dephosphorylation","year":2006,"lang":"en","type":"article","venue":"Biochemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging","keywords":"Dephosphorylation; Protein phosphatase 2; Phosphorylation; Heterotrimeric G protein; Protein subunit; Phosphatase; Protein kinase A; Serine; Chemistry; Cell biology; Cav1.2; Biochemistry; Biology; Signal transduction; G protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002317118,0.0006098258,0.0004108002,0.0002078118,0.0004028257,0.0007391925,0.0002719746,0.0003434239,0.004137688],"category_scores_gemma":[0.0003417738,0.0003223879,0.00048161,0.0001416943,0.0003450245,0.0002743307,0.0005000228,0.0007522503,0.00189066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007555247,"about_ca_system_score_gemma":0.0005231772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001480157,"about_ca_topic_score_gemma":0.00212723,"domain_scores_codex":[0.9996854,0.00003075146,0.00001647755,0.0001070369,0.00008040298,0.00007994485],"domain_scores_gemma":[0.9999241,0.000009335086,0.00001838934,0.000007600156,0.00001521738,0.00002543842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004052694,0.0001055326,0.000946706,0.0002770118,0.00004572366,0.0001629254,0.00003467579,0.0002965323,0.9861631,0.001338381,0.001324433,0.008899729],"study_design_scores_gemma":[0.0001206664,0.0004385808,0.01083385,0.00002538271,0.00003469934,0.0006517473,0.0000602033,0.004335659,0.9394933,0.0009501706,0.04303239,0.00002336107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.865016,0.06550711,0.03425729,0.002513904,0.001318093,0.0003962611,0.001324838,0.001008519,0.02865806],"genre_scores_gemma":[0.9702852,0.007614126,0.005821924,0.0004493245,0.0001801555,0.0001851785,0.001054691,0.00005718783,0.01435209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004137688,"threshold_uncertainty_score":0.01384199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01769320737324831,"score_gpt":0.2618031023001968,"score_spread":0.2441098949269485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}