{"id":"W2079827686","doi":"10.1021/bi051593z","title":"Binding of Protein Phosphatase 2A to the L-Type Calcium Channel Ca <sub>v</sub> 1.2 next to Ser1928, Its Main PKA Site, Is Critical for Ser1928 Dephosphorylation","year":2006,"lang":"en","type":"article","venue":"Biochemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging","keywords":"Dephosphorylation; Protein phosphatase 2; Phosphorylation; Heterotrimeric G protein; Protein subunit; Phosphatase; Protein kinase A; Serine; Chemistry; Cell biology; Cav1.2; Biochemistry; Biology; Signal transduction; G protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002369705,0.0002350394,0.0001686879,0.00004983071,0.0001782095,0.00004697203,0.000178923,0.0002922378,0.00003127298],"category_scores_gemma":[0.0002731094,0.0002164531,0.000121975,0.0002962221,0.00004541833,0.0000109079,0.00009938996,0.00008376197,0.00005164089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005396698,"about_ca_system_score_gemma":0.0001105214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002759806,"about_ca_topic_score_gemma":0.00001276292,"domain_scores_codex":[0.998552,0.00002540715,0.0003374946,0.0004926617,0.0002272854,0.0003651752],"domain_scores_gemma":[0.9989881,0.00002289978,0.00009440768,0.0003822911,0.0003555978,0.000156686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003466711,0.00006956651,0.00004798889,0.0001091577,0.00001614269,0.000001026814,0.00003570538,0.0003460036,0.9663261,0.00008854643,0.03214383,0.0004692267],"study_design_scores_gemma":[0.0003762205,0.0001838866,0.00017925,0.00004924322,0.00002239094,0.000007366638,0.0001102926,0.001048,0.9816414,0.00002462507,0.01609467,0.0002626547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984479,0.000559377,0.01136198,0.001732335,0.0003501735,0.0008001179,0.0005496485,0.00002362628,0.0001437103],"genre_scores_gemma":[0.9953442,0.000008147209,0.0004499818,0.0005831745,0.000941222,0.0001652556,0.001128585,0.00003993605,0.001339515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01604915,"threshold_uncertainty_score":0.8826699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01769320737324831,"score_gpt":0.2618031023001968,"score_spread":0.2441098949269485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}