{"id":"W2079876525","doi":"10.1371/journal.pntd.0002381","title":"Metabonomics Reveals Drastic Changes in Anti-Inflammatory/Pro-Resolving Polyunsaturated Fatty Acids-Derived Lipid Mediators in Leprosy Disease","year":2013,"lang":"en","type":"article","venue":"PLoS neglected tropical diseases","topic":"Leprosy Research and Treatment","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; University of British Columbia; Canada's Michael Smith Genome Sciences Centre","funders":"Canadian Institutes of Health Research; Genome Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Genome British Columbia; Foundation for Scientific and Technological Development in Health","keywords":"Leprosy; Polyunsaturated fatty acid; Lipid metabolism; Biology; Lipidomics; Metabolome; Immunology; Disease; Fatty acid; Medicine; Metabolomics; Bioinformatics; Biochemistry; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002703598,0.0004187921,0.0005032667,0.0009856265,0.0002453267,0.0005077416,0.0001113128,0.0003891406,0.0007991209],"category_scores_gemma":[0.0002486712,0.0001839555,0.0003367847,0.0007264782,0.0001976089,0.0002270356,0.0003494195,0.000302661,0.0002191767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001308344,"about_ca_system_score_gemma":0.0001832514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006053359,"about_ca_topic_score_gemma":0.000961397,"domain_scores_codex":[0.9998417,0.00003408654,0.00001622441,0.00004872508,0.00003193062,0.00002729814],"domain_scores_gemma":[0.9998524,0.0000206424,0.00006046842,0.00001225299,0.00002853598,0.00002571185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001167748,0.00004693533,0.03741282,0.0003004175,0.0001352068,0.0004772572,0.0002209871,0.0001702146,0.943669,0.0001005508,0.000157788,0.016141],"study_design_scores_gemma":[0.00003587265,0.001310753,0.849218,0.0001279276,0.0003884991,0.003066999,0.000697014,0.001602338,0.1365833,0.00113468,0.005764793,0.0000697724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9781544,0.012712,0.005618575,0.0002727313,0.00005707732,0.00005094964,0.002136114,0.00008105077,0.0009171577],"genre_scores_gemma":[0.9855215,0.005091396,0.006527088,0.0002860916,0.00003845004,0.0000424594,0.001312448,0.00001912354,0.001161387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009856265,"threshold_uncertainty_score":0.002673328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0158382715959299,"score_gpt":0.2507550431895737,"score_spread":0.2349167715936438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}