{"id":"W2079917842","doi":"10.1158/1538-7445.am2012-2532","title":"Abstract 2532: Integrated therapeutic antibody development at the National Research Council of Canada","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Antibody; Monoclonal antibody; Computational biology; Panning (audio); Immunization; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004771326,0.000936211,0.0006147047,0.001676465,0.002647942,0.002660712,0.002312414,0.001485936,0.0669494],"category_scores_gemma":[0.002078078,0.0005260993,0.0004498395,0.001175553,0.0009917865,0.0005867115,0.001469747,0.001682256,0.01897196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.02526855,"about_ca_system_score_gemma":0.09228655,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.7526591,"about_ca_topic_score_gemma":0.7887015,"domain_scores_codex":[0.9961609,0.0002266018,0.00006195805,0.0003050363,0.002625607,0.0006198947],"domain_scores_gemma":[0.9910448,0.0002096531,0.0001274246,0.000203367,0.00599709,0.002417617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007562311,0.0004721919,0.004502321,0.0004220884,0.00005177257,0.000608851,0.0003221391,0.002077118,0.06459184,0.02109577,0.7296315,0.1754682],"study_design_scores_gemma":[0.0001273009,0.0002211081,0.004497161,0.00007851155,0.00001742873,0.0001313321,0.0001025773,0.002381545,0.008401964,0.0005659701,0.9834426,0.00003249444],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0368711,0.02031359,0.05215938,0.03997622,0.005688952,0.003869401,0.03135648,0.009557064,0.8002079],"genre_scores_gemma":[0.07995868,0.008917745,0.04730714,0.004549403,0.0002679362,0.0006513817,0.0195678,0.0007939258,0.8379861],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.7526591,"threshold_uncertainty_score":0.4975951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3682078230712844,"score_gpt":0.4825595258693855,"score_spread":0.1143517027981011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}