{"id":"W2080019292","doi":"10.1186/s12951-014-0059-z","title":"Carbohydrate functionalization of silver nanoparticles modulates cytotoxicity and cellular uptake","year":2014,"lang":"en","type":"article","venue":"Journal of Nanobiotechnology","topic":"Nanoparticles: synthesis and applications","field":"Materials Science","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"Division of Materials Research; Max-Planck-Gesellschaft; Bundesanstalt für Materialforschung und -Prüfung","keywords":"Chemistry; Ethylene glycol; Protein Carbonylation; Oxidative stress; Cytotoxicity; Toxicity; Monosaccharide; Nanotoxicology; Silver nanoparticle; Mannose; Biochemistry; Carbohydrate; Nanoparticle; Biophysics; In vitro; Nanotechnology; Organic chemistry; Oxidative damage; Materials science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005135995,0.00009018332,0.0002565068,0.00013822,0.00007511096,0.00001840591,0.0001695876,0.0001390746,0.00006384547],"category_scores_gemma":[0.0001591889,0.00007248522,0.00005129369,0.0002064827,0.0002165015,0.0001247394,0.0000486226,0.00008307416,0.00001034132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001854645,"about_ca_system_score_gemma":0.0000257673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007812186,"about_ca_topic_score_gemma":0.000002541362,"domain_scores_codex":[0.9990074,0.00005977092,0.0004963789,0.0001335603,0.000151097,0.0001518036],"domain_scores_gemma":[0.9990768,0.00007949591,0.0004523246,0.0001842323,0.0001566206,0.00005054912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001880399,0.00007340555,0.0003877217,0.00001118158,0.000008939543,0.000001149448,0.00002869346,0.00025083,0.9898649,0.007972184,0.0000237724,0.001358419],"study_design_scores_gemma":[0.0002507988,0.0001595288,0.001522839,0.00002402045,0.00003285414,0.00003111763,0.00003577493,0.00122059,0.9907994,0.005063538,0.0007897373,0.00006985704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939688,0.0002737175,0.004745141,0.000799659,0.00009560957,0.00006824688,0.000004344814,0.00002478661,0.00001963705],"genre_scores_gemma":[0.9975154,0.00004178636,0.00234369,0.00003254883,0.0000413217,0.000003086776,4.293058e-7,0.000008705982,0.00001301712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003546557,"threshold_uncertainty_score":0.2955861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009875768080662373,"score_gpt":0.2117335877151447,"score_spread":0.2018578196344824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}