{"id":"W2080019292","doi":"10.1186/s12951-014-0059-z","title":"Carbohydrate functionalization of silver nanoparticles modulates cytotoxicity and cellular uptake","year":2014,"lang":"en","type":"article","venue":"Journal of Nanobiotechnology","topic":"Nanoparticles: synthesis and applications","field":"Materials Science","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"Division of Materials Research; Max-Planck-Gesellschaft; Bundesanstalt für Materialforschung und -Prüfung","keywords":"Chemistry; Ethylene glycol; Protein Carbonylation; Oxidative stress; Cytotoxicity; Toxicity; Monosaccharide; Nanotoxicology; Silver nanoparticle; Mannose; Biochemistry; Carbohydrate; Nanoparticle; Biophysics; In vitro; Nanotechnology; Organic chemistry; Oxidative damage; Materials science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001079578,0.0002724339,0.0001298311,0.0001185628,0.00007907128,0.0001996859,0.0001357914,0.0002043747,0.0006939565],"category_scores_gemma":[0.0001849053,0.00007909617,0.0001472175,0.000108957,0.0001674328,0.0001132771,0.0001096592,0.0002004981,0.0001696385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002413927,"about_ca_system_score_gemma":0.0001250892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006242478,"about_ca_topic_score_gemma":0.0006499595,"domain_scores_codex":[0.9999104,0.00001539041,0.000007364628,0.00001456984,0.00002434634,0.0000279406],"domain_scores_gemma":[0.9998969,0.00002764749,0.00002648831,0.00001048898,0.00002358862,0.00001492443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006033504,0.000008780049,0.0001003107,0.0000152084,0.000001758862,0.00001826074,0.000005478476,0.00002957555,0.9993381,0.00001517896,0.000008221635,0.0003988152],"study_design_scores_gemma":[0.000003233844,0.0001279301,0.001315768,0.000002184175,0.000006722988,0.0000354224,0.000007268707,0.0002518912,0.9979203,0.00001181216,0.0003153532,0.000002152282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982235,0.000408242,0.0006131618,0.0000234183,0.000009989693,0.000008092007,0.00005125947,0.00001351251,0.0006489306],"genre_scores_gemma":[0.9983717,0.0003023657,0.0006366255,0.00002288373,0.000004136908,0.00001063851,0.00008390903,0.000009287098,0.0005584932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006939565,"threshold_uncertainty_score":0.002321482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009875768080662373,"score_gpt":0.2117335877151447,"score_spread":0.2018578196344824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}