{"id":"W2080026750","doi":"10.1016/s0162-3109(00)80157-5","title":"Two clusters of acidic amino acids near the NH2-terminus of C4 α′-chain are important for C2 binding","year":2000,"lang":"en","type":"article","venue":"Immunopharmacology","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Amino acid; Biochemistry; Stereochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001744172,0.0005934389,0.0003892391,0.000223602,0.0005385058,0.0003673037,0.0004275794,0.0006540019,0.003539382],"category_scores_gemma":[0.0003172023,0.0002221123,0.0004422459,0.0001543195,0.0003933953,0.0004000987,0.0003984837,0.0007121012,0.001431528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005230518,"about_ca_system_score_gemma":0.0003926239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001349611,"about_ca_topic_score_gemma":0.0009236711,"domain_scores_codex":[0.9998575,0.00001794024,0.000009625319,0.00004165689,0.00002837872,0.0000447602],"domain_scores_gemma":[0.9996237,0.00006949566,0.0000735993,0.00003868776,0.00005965604,0.0001347441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007663324,0.00003012492,0.0007061091,0.00005560709,0.00001135347,0.000447484,0.00003594381,0.0001944884,0.994953,0.0003775916,0.0001174743,0.00230444],"study_design_scores_gemma":[0.00008519772,0.0002715191,0.01725125,0.00001265839,0.00003544434,0.001729278,0.00009627615,0.001251643,0.9734882,0.0003274289,0.005424137,0.00002701843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745953,0.001026637,0.01850301,0.0002187277,0.0001280927,0.0001107247,0.0005060692,0.0001591008,0.004752308],"genre_scores_gemma":[0.9851609,0.0002613327,0.009129679,0.0001602635,0.0000352052,0.0000563112,0.001064,0.000030161,0.004102056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003539382,"threshold_uncertainty_score":0.0118404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009292248984672066,"score_gpt":0.2771187877686171,"score_spread":0.267826538783945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}