{"id":"W2080070167","doi":"10.1021/bi0265473","title":"Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP1-Binding Sites of RAP74 and Human TFIIB<sup>,</sup>","year":2003,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences","keywords":"Transcription factor II B; Transcription factor II A; Transcription factor II F; Biochemistry; Binding site; Transcription preinitiation complex; Biology; Chemistry; Biophysics; Cell biology; Transcription factor; RNA polymerase; Transcriptional regulation; RNA; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009822465,0.000367489,0.0002142503,0.0001846482,0.0003709868,0.0001455622,0.0005900807,0.0003824982,0.002049094],"category_scores_gemma":[0.0002773429,0.0001714563,0.0002658871,0.0003104634,0.0002508237,0.0001698486,0.0001159795,0.0005252921,0.0004474892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000856875,"about_ca_system_score_gemma":0.000320835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004973474,"about_ca_topic_score_gemma":0.004027689,"domain_scores_codex":[0.999933,0.000009435747,0.000002464943,0.00001392332,0.0000236615,0.00001740548],"domain_scores_gemma":[0.999881,0.00002995946,0.00002654208,0.00000697788,0.00002684606,0.00002867615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004113503,0.00007077007,0.0007986414,0.0001243536,0.00004072282,0.000212577,0.00009248265,0.003913862,0.9887842,0.0006782003,0.0009331625,0.003939627],"study_design_scores_gemma":[0.0001475114,0.0004023716,0.02233649,0.00003812152,0.0001193539,0.0006698514,0.0003068032,0.02981795,0.9294297,0.0005115311,0.01615836,0.00006198602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914727,0.001479627,0.003350114,0.0003102869,0.00002485375,0.00001728945,0.0007830828,0.00007151996,0.002490564],"genre_scores_gemma":[0.9813086,0.001293564,0.008437964,0.0001829621,0.00003381593,0.00004292956,0.00610159,0.0000443121,0.002554124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004973474,"threshold_uncertainty_score":0.009889066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00608023044784863,"score_gpt":0.2177530042583002,"score_spread":0.2116727738104515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}