{"id":"W2080070167","doi":"10.1021/bi0265473","title":"Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP1-Binding Sites of RAP74 and Human TFIIB<sup>,</sup>","year":2003,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences","keywords":"Transcription factor II B; Transcription factor II A; Transcription factor II F; Biochemistry; Binding site; Transcription preinitiation complex; Biology; Chemistry; Biophysics; Cell biology; Transcription factor; RNA polymerase; Transcriptional regulation; RNA; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009088853,0.0001021617,0.0001372774,0.00001543697,0.00006868142,0.000005046165,0.0001320774,0.000153436,0.00001027739],"category_scores_gemma":[0.00003338337,0.00007304571,0.00006095207,0.00008952714,0.0002918807,0.000003767868,0.0000617933,0.00005852748,1.559892e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007933809,"about_ca_system_score_gemma":0.0000617432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001101151,"about_ca_topic_score_gemma":0.000002318786,"domain_scores_codex":[0.9993358,0.00004311867,0.0002414868,0.0001753564,0.0001139327,0.00009033764],"domain_scores_gemma":[0.9992386,0.00000536654,0.0003017657,0.0003389613,0.00009313497,0.00002218847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001593069,0.00002322589,0.01791636,0.0001571811,0.00002658178,4.3433e-8,0.0001022103,0.000005121276,0.9815136,0.0001101703,0.00001940498,0.0001101494],"study_design_scores_gemma":[0.0002883901,0.00003204703,0.02295364,0.00005179762,0.00003102368,0.000008833479,0.0001484996,0.00001824843,0.9762208,0.00004424819,0.0001326491,0.00006986457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991044,0.0004263797,0.00003715071,0.0000261811,0.00001913765,0.0001120095,0.000146491,0.000001290344,0.000126944],"genre_scores_gemma":[0.999608,0.00006947404,0.00008480219,0.000008478454,0.00003356938,0.00000329967,0.00006474848,0.000007461672,0.0001202011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00529286,"threshold_uncertainty_score":0.2978718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00608023044784863,"score_gpt":0.2177530042583002,"score_spread":0.2116727738104515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}