{"id":"W2080078056","doi":"10.1016/j.bcp.2008.12.016","title":"Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to Adriamycin","year":2009,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Medical Research and Materiel Command; National Cancer Institute; Virginia Commonwealth University","keywords":"Senescence; Autophagy; Apoptosis; Programmed cell death; Reactive oxygen species; Biology; Cell biology; Cancer research; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002179019,0.0001962223,0.0003340693,0.0003967928,0.0002452593,0.0003019325,0.0001626903,0.0002728433,0.0008234023],"category_scores_gemma":[0.0002107785,0.0001890633,0.0002265959,0.000420247,0.0002391228,0.0001957107,0.0001093944,0.0004841226,0.0001873226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004595314,"about_ca_system_score_gemma":0.0003262609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00204769,"about_ca_topic_score_gemma":0.002208543,"domain_scores_codex":[0.9998635,0.00003789657,0.00001655831,0.00001380188,0.00002982853,0.00003841872],"domain_scores_gemma":[0.9998896,0.00003631815,0.00001897894,0.00002248487,0.0000173258,0.00001529556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003163423,0.0001438388,0.001164812,0.00007516842,0.00002171072,0.0002735136,0.00009826181,0.0003613103,0.9910347,0.0002797842,0.0001161919,0.003267199],"study_design_scores_gemma":[0.000121614,0.000855917,0.0141499,0.000007821223,0.00003025289,0.0004606098,0.0000988461,0.0009705907,0.9811946,0.0001329062,0.001969943,0.000006924985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953576,0.00276646,0.0003744161,0.0001240751,0.00002484573,0.00001656921,0.0002860322,0.00003527265,0.001014719],"genre_scores_gemma":[0.9966844,0.00116267,0.0003266546,0.00003589438,0.00001076185,0.00002567924,0.000357271,0.000005676929,0.001390943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00204769,"threshold_uncertainty_score":0.004071593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01093700954047946,"score_gpt":0.2959892561775743,"score_spread":0.2850522466370949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}