{"id":"W2080086829","doi":"10.1016/s0165-5728(03)00132-2","title":"Bilirubin as a potent antioxidant suppresses experimental autoimmune encephalomyelitis: implications for the role of oxidative stress in the development of multiple sclerosis","year":2003,"lang":"en","type":"article","venue":"Journal of Neuroimmunology","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver Hospital and Health Sciences Centre; University of British Columbia Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society","keywords":"Experimental autoimmune encephalomyelitis; Oxidative stress; Multiple sclerosis; Antioxidant; Encephalomyelitis; Bilirubin; Medicine; Immunology; Chemistry; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003421164,0.0001200997,0.0002229782,0.00006982542,0.00007803934,0.000008756418,0.0004150213,0.0000763978,0.000006764938],"category_scores_gemma":[0.0003133695,0.00007707928,0.0001390632,0.0001097127,0.0001579644,0.000008411238,0.00005857218,0.0001202986,3.383939e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001533859,"about_ca_system_score_gemma":0.0002187208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002085804,"about_ca_topic_score_gemma":0.00001983223,"domain_scores_codex":[0.9987428,0.0002074794,0.0006184302,0.0001419935,0.0001058204,0.0001834558],"domain_scores_gemma":[0.9989021,0.0001753671,0.0004271708,0.000298767,0.0001764186,0.00002011369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000150059,0.0003484046,0.002470878,0.000006514324,0.00009888993,8.832623e-7,0.0008563513,0.00007640971,0.9935367,0.0003548659,0.00001511761,0.002084977],"study_design_scores_gemma":[0.0006491487,0.00045424,0.2326144,0.00002330553,0.00001606812,0.00005424791,0.004099966,0.000005134568,0.7596342,0.00009893455,0.002291007,0.00005933461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916129,0.007389125,0.0003103287,0.0002271218,0.00008424475,0.0002730679,0.00002397389,0.000001336822,0.00007789928],"genre_scores_gemma":[0.9982346,0.000451726,0.001167865,0.00004968487,0.00001813846,0.00005125053,0.00000597349,0.00001117416,0.000009534783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2339025,"threshold_uncertainty_score":0.3143201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02644798682127206,"score_gpt":0.2679760679412892,"score_spread":0.2415280811200171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}