{"id":"W2080092936","doi":"10.1002/eji.200838373","title":"Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3","year":2008,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"","keywords":"FOXP3; Effector; Biology; Reprogramming; Cell biology; Regulator; Phenotype; Regulatory T cell; Downregulation and upregulation; Secretion; Immunology; Cell; IL-2 receptor; T cell; Immune system; Gene; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002010864,0.000285017,0.0001798122,0.0001650428,0.0001005887,0.000232784,0.0001535489,0.0001741706,0.001309288],"category_scores_gemma":[0.0001505726,0.0001145076,0.0002181085,0.0001522156,0.0002609972,0.0001083994,0.0002080721,0.000478414,0.0003046008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009072839,"about_ca_system_score_gemma":0.0001709618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002181403,"about_ca_topic_score_gemma":0.0003686772,"domain_scores_codex":[0.9998417,0.0000287164,0.00001620051,0.00003673104,0.00003454661,0.00004203446],"domain_scores_gemma":[0.9998823,0.00003398549,0.0000303822,0.00002688981,0.00000804728,0.00001828987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004165031,0.00000920928,0.00007816765,0.0000130248,0.000001878443,0.00004133335,0.00001087078,0.00005049487,0.9985123,0.0001313718,0.00002264008,0.001087037],"study_design_scores_gemma":[0.00002695766,0.0002308758,0.001330812,0.000005054135,0.000017392,0.0003605836,0.0000193588,0.0008349545,0.9923212,0.00009011229,0.004757868,0.000004857085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9629832,0.000939214,0.03219768,0.00008958303,0.0001091911,0.0001162504,0.0007118538,0.0003785835,0.002474523],"genre_scores_gemma":[0.9880832,0.0004338821,0.0085868,0.00004772069,0.00001875598,0.0000573683,0.0005020534,0.00006303151,0.002207216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001309288,"threshold_uncertainty_score":0.004379988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01478824207504439,"score_gpt":0.2303797992160239,"score_spread":0.2155915571409796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}