{"id":"W2080118521","doi":"10.1172/jci57755","title":"In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; State Government of Victoria; National Health and Medical Research Council; University of California, San Diego; National Institutes of Health; National Heart, Lung, and Blood Institute; Australian Government","keywords":"Zebrafish; Epitope; Oxidative stress; In vivo; Heat shock protein; Malondialdehyde; Green fluorescent protein; Monoclonal antibody; Transgene; Antibody; Chemistry; Biology; Molecular biology; Biochemistry; Cell biology; Immunology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001817534,0.00007518318,0.000379428,0.0001585211,0.00001551033,0.000005522409,0.00007216694,0.000205103,0.00005382718],"category_scores_gemma":[0.0008056172,0.00006624717,0.0001266297,0.0001482803,0.0001499378,0.0003784878,0.00001837918,0.0001830439,0.000003001717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001739367,"about_ca_system_score_gemma":0.00006014554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004104317,"about_ca_topic_score_gemma":0.00002443416,"domain_scores_codex":[0.9978822,0.0006346352,0.001220018,0.0001149884,0.00006482196,0.00008334128],"domain_scores_gemma":[0.9988606,0.0001751553,0.0007057518,0.00009135489,0.0001384128,0.00002870446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003421447,0.000214456,0.6908434,0.00002485608,0.00006491333,0.000001273404,0.001136548,0.00003887389,0.3042639,0.0004236687,0.000142586,0.002503397],"study_design_scores_gemma":[0.003132574,0.0002131942,0.9482198,0.0001950757,0.00006188454,0.000008705543,0.0001680562,0.00008686135,0.04621316,0.001511451,0.0001196999,0.00006954228],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987233,0.0004172095,0.0003560011,0.00006283615,0.0002926558,0.0001071108,0.000002119803,0.000003494353,0.00003529973],"genre_scores_gemma":[0.9992574,0.0003099768,0.0001819717,0.0001725149,0.00005257405,0.000002179599,0.000006386615,0.000007096895,0.000009850895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2580507,"threshold_uncertainty_score":0.2701481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1294203646613644,"score_gpt":0.3644482974323751,"score_spread":0.2350279327710107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}