{"id":"W2080240672","doi":"10.1016/j.jim.2010.09.010","title":"A simple two-step purification procedure for the iC3b binding collectin conglutinin","year":2010,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"iC3b; Collectin; Mannan; Complement system; Antibody opsonization; Ficolin; Chemistry; Chromatography; Lectin; Affinity chromatography; Biochemistry; Mannan-binding lectin; Biology; Innate immune system; Antibody; Polysaccharide; Opsonin; Immunology; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.003755847,0.0001889611,0.0004586569,0.0001402142,0.0004955993,0.00005220971,0.0006984076,0.0002328548,0.0009668368],"category_scores_gemma":[0.00637884,0.0001074717,0.0003132983,0.0002623485,0.0002640033,0.00009455752,0.0001043738,0.0008061859,0.00002999531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004774964,"about_ca_system_score_gemma":0.0001483618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007011134,"about_ca_topic_score_gemma":0.000006912648,"domain_scores_codex":[0.9975905,0.0009318182,0.0008471907,0.0002034441,0.00006504232,0.0003619487],"domain_scores_gemma":[0.9938159,0.004513593,0.0009220042,0.0003253821,0.0003928943,0.00003025739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006072206,0.0001751698,0.001524944,0.00001881068,0.0003834786,0.000001855705,0.0001102743,0.000006621905,0.9565269,0.00282868,0.005519213,0.03229684],"study_design_scores_gemma":[0.007231656,0.001906678,0.044406,0.00009171521,0.0005537617,0.001127449,0.002983808,0.0001541098,0.3983821,0.004232955,0.5384402,0.0004895543],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9402068,0.007922607,0.04408478,0.001877403,0.003840283,0.001443631,0.00005265613,0.00006970405,0.0005020972],"genre_scores_gemma":[0.933229,0.0000582261,0.06558517,0.0001249508,0.0001977599,0.0001217725,0.00001551365,0.00001946851,0.0006481334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5581448,"threshold_uncertainty_score":0.9999464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05356609586698712,"score_gpt":0.4001483279521976,"score_spread":0.3465822320852105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}