{"id":"W2080294842","doi":"10.1371/journal.pgen.1001366","title":"Genome Analysis Reveals Interplay between 5′UTR Introns and Nuclear mRNA Export for Secretory and Mitochondrial Genes","year":2011,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"National Human Genome Research Institute; Canada Excellence Research Chairs, Government of Canada; National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Canadian Institute for Advanced Research; Howard Hughes Medical Institute","keywords":"Biology; Intron; RNA splicing; Untranslated region; Genetics; Nuclear export signal; Gene; Coding region; Messenger RNA; Three prime untranslated region; Computational biology; RNA; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001228482,0.0001635357,0.000261271,0.0001095034,0.0001126311,0.00003686942,0.0001754421,0.00015349,0.00003043315],"category_scores_gemma":[0.0000551633,0.0001578043,0.00009897695,0.00008698168,0.0001269713,0.000004231854,0.0002045905,0.00007933796,0.000002427043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009691609,"about_ca_system_score_gemma":0.00003027469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008038763,"about_ca_topic_score_gemma":0.00002438588,"domain_scores_codex":[0.9988665,0.00004682294,0.0002383991,0.0004078607,0.0001191072,0.0003212962],"domain_scores_gemma":[0.9992718,0.00002138497,0.00007508093,0.0003226445,0.00008844741,0.0002206974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009274205,0.00002806578,0.04166166,0.00003537022,0.000724459,0.000002687753,0.0002268031,0.000001756609,0.956082,0.00001394266,0.0001153758,0.001015165],"study_design_scores_gemma":[0.00343101,0.003777757,0.2530173,0.0000489471,0.003051586,0.00002718782,0.000986119,0.002972521,0.7017852,0.0005958364,0.02865273,0.00165383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962212,0.001909334,0.0012098,0.00002626872,0.00003580325,0.0003191627,0.00009010828,0.00001012969,0.0001781931],"genre_scores_gemma":[0.9914135,0.0008542841,0.006630634,0.00006231553,0.0004735471,0.00003004104,0.0001148153,0.00003596961,0.0003849217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2542968,"threshold_uncertainty_score":0.6435072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02797937931114299,"score_gpt":0.2776143444993702,"score_spread":0.2496349651882272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}