{"id":"W2080294842","doi":"10.1371/journal.pgen.1001366","title":"Genome Analysis Reveals Interplay between 5′UTR Introns and Nuclear mRNA Export for Secretory and Mitochondrial Genes","year":2011,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"National Human Genome Research Institute; Canada Excellence Research Chairs, Government of Canada; National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Canadian Institute for Advanced Research; Howard Hughes Medical Institute","keywords":"Biology; Intron; RNA splicing; Untranslated region; Genetics; Nuclear export signal; Gene; Coding region; Messenger RNA; Three prime untranslated region; Computational biology; RNA; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001266432,0.0001140525,0.0001685897,0.0003470802,0.0001233772,0.0002358766,0.0001191407,0.0001660272,0.000365203],"category_scores_gemma":[0.0002334697,0.00009910565,0.0002038205,0.0003288804,0.0001166819,0.0001180461,0.0001328871,0.0002892141,0.0001256189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001449327,"about_ca_system_score_gemma":0.000127268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005228611,"about_ca_topic_score_gemma":0.001192241,"domain_scores_codex":[0.9999127,0.00001821188,0.000006695203,0.00003265567,0.00001864101,0.00001114268],"domain_scores_gemma":[0.9997873,0.00007893355,0.0000778684,0.00001569994,0.00001460124,0.00002563193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002287832,0.0000197576,0.008331398,0.00004306863,0.00001702328,0.0001191361,0.00003695365,0.0001805323,0.9873207,0.0001857607,0.00003491705,0.003481902],"study_design_scores_gemma":[0.00003665786,0.0003497956,0.5834056,0.00002499659,0.0002368902,0.001147296,0.000159876,0.009227546,0.398148,0.0009432327,0.00629266,0.00002737502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964151,0.0005216672,0.002331109,0.00003294771,0.000002878741,0.00000323768,0.0003528063,0.00003248305,0.0003077835],"genre_scores_gemma":[0.9913279,0.0003694783,0.005641167,0.00004504172,0.000004695245,0.000008644316,0.002143728,0.00002467012,0.0004345017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005228611,"threshold_uncertainty_score":0.001221716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02797937931114299,"score_gpt":0.2776143444993702,"score_spread":0.2496349651882272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}