{"id":"W2080323821","doi":"10.1210/en.2005-0606","title":"Elevated Circulating Insulin-Like Growth Factor Binding Protein-1 Is Sufficient to Cause Fetal Growth Restriction","year":2005,"lang":"en","type":"article","venue":"Endocrinology","topic":"Birth, Development, and Health","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Canadian Institutes of Health Research; Western University; Mount Sinai Hospital","funders":"","keywords":"Internal medicine; Endocrinology; Fetus; Insulin-like growth factor-binding protein; Biology; Placenta; Somatomedin; Insulin-like growth factor; Growth factor; Transgene; Genetically modified mouse; Insulin-like growth factor 2; Gene; Receptor; Hormone; Pregnancy; Growth hormone; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002634721,0.000695191,0.0006324478,0.0007197501,0.0001518198,0.0003961686,0.0004318091,0.0005679129,0.001872081],"category_scores_gemma":[0.0005722056,0.0003343873,0.0002793771,0.0002633616,0.000828711,0.0002663641,0.0004525651,0.001219498,0.0003766034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005256244,"about_ca_system_score_gemma":0.0003405537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008104132,"about_ca_topic_score_gemma":0.0008417479,"domain_scores_codex":[0.999587,0.0000587397,0.00004931909,0.0000829618,0.0001401508,0.00008181733],"domain_scores_gemma":[0.9991689,0.0001822708,0.0002701017,0.00007740677,0.00003415788,0.0002671558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009640396,0.0001981997,0.001011949,0.0001080808,0.00002150144,0.0006775978,0.00003002614,0.0001068687,0.9932427,0.0002251767,0.0001774311,0.003236338],"study_design_scores_gemma":[0.0003152765,0.004907151,0.032359,0.00005385305,0.0001433114,0.006626648,0.0001306514,0.001787998,0.946779,0.0004214486,0.006444721,0.00003091223],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942029,0.001733307,0.002014803,0.0001939415,0.00007336275,0.00003609634,0.0005046381,0.0003045863,0.0009363067],"genre_scores_gemma":[0.9912327,0.001703037,0.002438612,0.000148003,0.00005403024,0.00010717,0.001084359,0.0001002875,0.00313181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001872081,"threshold_uncertainty_score":0.006262779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03861966742454223,"score_gpt":0.3006705267044695,"score_spread":0.2620508592799273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}