{"id":"W2080386276","doi":"10.1016/j.biopsych.2010.04.038","title":"Imaging Dopamine D3 Receptors in the Human Brain with Positron Emission Tomography, [11C]PHNO, and a Selective D3 Receptor Antagonist","year":2010,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":150,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"GlaxoSmithKline","keywords":"Raclopride; Dopamine receptor D3; Globus pallidus; Binding potential; Internal medicine; Substantia nigra; Agonist; Endocrinology; Chemistry; Dopamine receptor D2; Striatum; Receptor; Dopamine; Pharmacology; Medicine; Basal ganglia; Dopaminergic; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002841254,0.0003718933,0.0003807003,0.0001740748,0.0003995832,0.0003737096,0.0003535651,0.0007803288,0.00166659],"category_scores_gemma":[0.0003243799,0.0004364446,0.0001653037,0.0002333923,0.000626578,0.0003098217,0.0001497497,0.0005698995,0.0002642663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005563683,"about_ca_system_score_gemma":0.0007120934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008101065,"about_ca_topic_score_gemma":0.01427373,"domain_scores_codex":[0.9999268,0.00002911781,0.000002670937,0.00001402303,0.000008909503,0.00001843646],"domain_scores_gemma":[0.9999448,0.00002223527,0.000009258508,0.000006529424,0.000005476572,0.00001159584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02049347,0.000363683,0.007720868,0.00041203,0.0002737817,0.001501955,0.0002669609,0.001035308,0.9297496,0.001883105,0.001774395,0.03452488],"study_design_scores_gemma":[0.003344022,0.01357154,0.09717865,0.0000761052,0.0009812163,0.01450703,0.0009118069,0.01316245,0.8366737,0.003461786,0.01604225,0.00008940315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9658692,0.01052595,0.015025,0.001043915,0.00005760849,0.0001465078,0.0004179651,0.0001001908,0.00681373],"genre_scores_gemma":[0.9829985,0.004556994,0.008296988,0.000447504,0.0000287034,0.0001245552,0.0002072023,0.00003836444,0.003301112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008101065,"threshold_uncertainty_score":0.01610786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0174799346214449,"score_gpt":0.2839712387263304,"score_spread":0.2664913041048855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}