{"id":"W2080673452","doi":"10.1038/sj.onc.1210338","title":"SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas","year":2007,"lang":"en","type":"article","venue":"Oncogene","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Biology; Medulloblastoma; DNA methylation; Demethylating agent; Bisulfite sequencing; CpG site; Cancer research; Molecular biology; Methylation; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004875877,0.0001717268,0.0001584076,0.00009784179,0.00007238118,0.00002180436,0.0001180455,0.0002178874,0.00007718087],"category_scores_gemma":[0.00002422885,0.0001793972,0.00006301773,0.0001270978,0.00009039817,0.000003349501,0.00004591034,0.00008327108,0.000004992434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001987693,"about_ca_system_score_gemma":0.0000414669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004177092,"about_ca_topic_score_gemma":0.0005992949,"domain_scores_codex":[0.9986938,0.00004705772,0.0003598345,0.0004065362,0.0001755526,0.0003172346],"domain_scores_gemma":[0.9994492,0.00001253644,0.00006259065,0.0002446068,0.0000790205,0.0001520455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007076805,0.00007361879,0.00609225,0.0000091951,0.00002369827,0.000005477752,0.00008681093,0.0000373685,0.9837545,0.0001595528,0.00005232878,0.009634404],"study_design_scores_gemma":[0.000972228,0.0003423773,0.1042118,0.00001399604,0.00001512634,0.000005986773,0.00002478407,0.00004316715,0.871515,0.0007361547,0.02188009,0.0002393196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895144,0.003237697,0.004300855,0.0001942578,0.00008949281,0.0001749684,0.0000163774,0.00001070329,0.002461276],"genre_scores_gemma":[0.9961374,0.000378093,0.002297706,0.0002508407,0.0002071763,0.000007267027,0.0001207195,0.00002655245,0.0005742722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1122395,"threshold_uncertainty_score":0.7315608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00922861837240104,"score_gpt":0.2796765782436469,"score_spread":0.2704479598712459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}