{"id":"W2080700347","doi":"10.1128/aac.01802-09","title":"The BceABRS Four-Component System Regulates the Bacitracin-Induced Cell Envelope Stress Response in <i>Streptococcus mutans</i>","year":2010,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Operon; Bacitracin; Biology; Bacillus subtilis; Streptococcus mutans; Regulon; Two-component regulatory system; Gene; Lipid II; Genetics; Histidine kinase; Response regulator; Levansucrase; Microbiology; Regulation of gene expression; Escherichia coli; Bacteria; Peptidoglycan; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000391043,0.0002445339,0.0001817446,0.00003397936,0.0002922991,0.0001188109,0.000439558,0.0003479575,0.00001125146],"category_scores_gemma":[0.00001443365,0.0001494119,0.00007594803,0.0001215605,0.0002142478,0.000003826657,0.0001288217,0.0002714773,0.00000533911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001024055,"about_ca_system_score_gemma":0.00005580159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005176819,"about_ca_topic_score_gemma":0.0001613423,"domain_scores_codex":[0.9987113,0.00011009,0.0003003761,0.000410114,0.00009155815,0.0003765615],"domain_scores_gemma":[0.9991823,0.00003248859,0.0001284359,0.0005412541,0.00005560556,0.0000598578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005894472,0.00006086452,0.001893,0.00001451222,0.00003113943,0.000006138561,0.00007826974,0.000002402853,0.992289,0.00002204814,0.001414442,0.00359873],"study_design_scores_gemma":[0.0009080695,0.0001447878,0.03043295,0.00001937884,0.000008490849,0.00002268767,0.0001058374,0.00002487095,0.8647245,0.000007147392,0.1034003,0.0002009887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945626,0.00006281663,0.000008152956,0.004260361,0.000505758,0.000442809,0.00003012809,0.00001787906,0.0001094793],"genre_scores_gemma":[0.9974076,0.0009186832,0.00008706612,0.001073112,0.0001676715,0.00001934614,0.00002215782,0.00003218006,0.00027215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1275645,"threshold_uncertainty_score":0.6092839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005965653409556303,"score_gpt":0.2073259035492217,"score_spread":0.2013602501396654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}