{"id":"W2080700347","doi":"10.1128/aac.01802-09","title":"The BceABRS Four-Component System Regulates the Bacitracin-Induced Cell Envelope Stress Response in <i>Streptococcus mutans</i>","year":2010,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Operon; Bacitracin; Biology; Bacillus subtilis; Streptococcus mutans; Regulon; Two-component regulatory system; Gene; Lipid II; Genetics; Histidine kinase; Response regulator; Levansucrase; Microbiology; Regulation of gene expression; Escherichia coli; Bacteria; Peptidoglycan; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006786409,0.000367047,0.000205672,0.0002677699,0.0001653233,0.0002805751,0.0001132593,0.0001465996,0.001053557],"category_scores_gemma":[0.0001103573,0.0001124251,0.0002210959,0.0001194014,0.0001712553,0.0001163859,0.0002114591,0.0002494246,0.0004244302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004420505,"about_ca_system_score_gemma":0.0002191199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00183482,"about_ca_topic_score_gemma":0.001586503,"domain_scores_codex":[0.9998833,0.00001659839,0.000007013576,0.0000266303,0.00003897381,0.00002748486],"domain_scores_gemma":[0.9999403,0.00001013908,0.00001702548,0.000004781091,0.00001092126,0.00001674172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004269781,0.00001276431,0.000199953,0.00001154146,0.000001060136,0.00002227456,0.00001332491,0.00002739478,0.9989204,0.00004845577,0.00002525907,0.0006747899],"study_design_scores_gemma":[0.000009942307,0.0001044078,0.02728555,0.00000956914,0.000008538726,0.000193044,0.00008596185,0.002400053,0.9673344,0.00009754689,0.002463688,0.00000734601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957017,0.0006850996,0.001609911,0.0001091576,0.00001729584,0.00001784728,0.000396048,0.0001927815,0.0012701],"genre_scores_gemma":[0.9919379,0.0002923441,0.002064382,0.0000462522,0.000008113115,0.0000261741,0.001073346,0.00002937065,0.004522078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00183482,"threshold_uncertainty_score":0.003648281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005965653409556303,"score_gpt":0.2073259035492217,"score_spread":0.2013602501396654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}