{"id":"W2080728865","doi":"10.1016/j.placenta.2007.01.006","title":"2005 Trophoblast Research Award Lecture: Defects in the Keratin Cytoskeleton Disrupt Normal Murine Placental Development and Trophoblast Cell Function","year":2007,"lang":"en","type":"article","venue":"Placenta","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Trophoblast; Cell biology; Keratin 8; Biology; Placenta; Keratin; Syncytiotrophoblast; Cytoskeleton; Intermediate filament; Cell; Genetics; Fetus; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001396901,0.001199119,0.0005149242,0.0008200669,0.0009867874,0.0008962678,0.0008515875,0.002529435,0.02616483],"category_scores_gemma":[0.0007684691,0.0003463411,0.0005283542,0.0002136222,0.0005750454,0.000468619,0.0006866038,0.002080546,0.003867395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002142943,"about_ca_system_score_gemma":0.001550705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00220463,"about_ca_topic_score_gemma":0.006148785,"domain_scores_codex":[0.9996525,0.00004259155,0.00002160918,0.00007609191,0.0001160897,0.00009116437],"domain_scores_gemma":[0.9987161,0.00009652728,0.00005129382,0.00003248614,0.0002379426,0.0008655626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004313592,0.001248323,0.003329991,0.0003455229,0.0002127055,0.002238457,0.0002485313,0.001741945,0.2128976,0.01603841,0.6523122,0.1050727],"study_design_scores_gemma":[0.0007873842,0.003682944,0.0208487,0.0001688155,0.0002804045,0.002111947,0.0003224427,0.006464832,0.126419,0.004494539,0.8343208,0.00009817171],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.3365128,0.03403021,0.02173719,0.2258129,0.1670546,0.0009893797,0.003066606,0.00190745,0.2088889],"genre_scores_gemma":[0.2952472,0.008926656,0.01090666,0.006588808,0.0144477,0.0002178842,0.001784589,0.0002444638,0.6616361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02616483,"threshold_uncertainty_score":0.08753008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01476418566518214,"score_gpt":0.2788396043522537,"score_spread":0.2640754186870716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}