{"id":"W2080754850","doi":"10.1016/j.aquatox.2007.08.010","title":"Effects on reproductive potential and endocrine status in the mummichog (Fundulus heteroclitus) after exposure to 17α-ethynylestradiol in a short-term reproductive bioassay","year":2007,"lang":"en","type":"article","venue":"Aquatic Toxicology","topic":"Reproductive biology and impacts on aquatic species","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":false,"ca_institutions":"Environment and Climate Change Canada; Fisheries and Oceans Canada; University of New Brunswick","funders":"Networks of Centres of Excellence of Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Water Network","keywords":"Gonadosomatic Index; Vitellogenin; Fundulus; Biology; Bioassay; Endocrinology; Testosterone (patch); Endocrine system; Internal medicine; Endocrine disruptor; Estrogen; Gonad; Secondary sex characteristic; Hormone; Fish <Actinopterygii>; Population; Medicine; Ecology; Fecundity; Fishery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001086777,0.0003577085,0.0003289275,0.0003241088,0.000319116,0.0003227871,0.0001980886,0.0003932274,0.001050544],"category_scores_gemma":[0.0002820295,0.0002727567,0.0002839708,0.0001993695,0.0004429971,0.0002529089,0.0002418638,0.0004740974,0.0001797674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003377071,"about_ca_system_score_gemma":0.0002098381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003770171,"about_ca_topic_score_gemma":0.007923272,"domain_scores_codex":[0.9999057,0.0000171798,0.000009372424,0.00002437048,0.00001653859,0.00002675696],"domain_scores_gemma":[0.9997746,0.00004549166,0.00005281092,0.00002673435,0.00002657038,0.00007380259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005325925,0.0002980588,0.01451275,0.00003466296,0.00004857873,0.0002578357,0.000202034,0.0000937685,0.9764603,0.00003356313,0.00006292931,0.002669665],"study_design_scores_gemma":[0.0001369489,0.01098133,0.343564,0.00001245305,0.0002703067,0.0004468604,0.0008823236,0.0007976867,0.6413663,0.0001180038,0.001385225,0.00003866397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996021,0.00008715408,0.00005202134,0.00001551284,0.00000666666,0.000004889606,0.00007756539,0.000003971418,0.0001501378],"genre_scores_gemma":[0.9970951,0.0001681734,0.0001423208,0.00004823195,0.000008040214,0.00002714771,0.0003776862,0.000005737595,0.002127561],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003770171,"threshold_uncertainty_score":0.007496476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009786959275732997,"score_gpt":0.2744406639398424,"score_spread":0.2646537046641094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}