{"id":"W2080754894","doi":"10.1002/jcb.10515","title":"Phenotype discovery by gene expression profiling: Mapping of biological processes linked to BMP‐2‐mediated osteoblast differentiation","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health","keywords":"RUNX2; Osteoblast; Bone morphogenetic protein 2; Biology; Bone morphogenetic protein; Cell biology; Phenotype; Gene expression profiling; SMAD; Cellular differentiation; Gene; Transcription factor; Signal transduction; Gene expression; C2C12; Genetics; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000148957,0.0002524193,0.0003502217,0.0007277688,0.000164966,0.0003642991,0.0001716125,0.0003389032,0.0005274314],"category_scores_gemma":[0.0002800825,0.000145688,0.0001884717,0.0007802619,0.0002020192,0.0002353998,0.0001726349,0.0002952514,0.0003029974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001704512,"about_ca_system_score_gemma":0.0001544158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003419327,"about_ca_topic_score_gemma":0.0005294179,"domain_scores_codex":[0.9998522,0.00001926217,0.000006996963,0.00005494706,0.00004183191,0.00002470028],"domain_scores_gemma":[0.9998659,0.00003917271,0.00004139669,0.00001016917,0.00002383079,0.00001955971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006579178,0.00001573672,0.002383875,0.00004462844,0.000005090697,0.00002167484,0.00002254845,0.00004232228,0.9946655,0.00003545445,0.00003293433,0.002664387],"study_design_scores_gemma":[0.00001511687,0.0003913101,0.3473095,0.00001817852,0.00007047489,0.0005872375,0.0001839641,0.003283544,0.6447736,0.0003316231,0.003014908,0.00002056567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836662,0.00166609,0.01066363,0.00009364854,0.00001554187,0.00005782216,0.002515543,0.0001159277,0.001205506],"genre_scores_gemma":[0.9709733,0.002354194,0.02071066,0.0001630765,0.00003108828,0.0002852472,0.003230551,0.00004047942,0.002211329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007277688,"threshold_uncertainty_score":0.001764476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211180974874958,"score_gpt":0.2260588940356639,"score_spread":0.2139470842869143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}