{"id":"W2080754894","doi":"10.1002/jcb.10515","title":"Phenotype discovery by gene expression profiling: Mapping of biological processes linked to BMP‐2‐mediated osteoblast differentiation","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health","keywords":"RUNX2; Osteoblast; Bone morphogenetic protein 2; Biology; Bone morphogenetic protein; Cell biology; Phenotype; Gene expression profiling; SMAD; Cellular differentiation; Gene; Transcription factor; Signal transduction; Gene expression; C2C12; Genetics; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002474299,0.0002325762,0.0002999821,0.00006194972,0.00005814338,0.00004241036,0.0003087611,0.0002739169,0.0000230744],"category_scores_gemma":[0.001337252,0.0001915126,0.0001468451,0.0001843001,0.00007386001,0.000012678,0.00008018132,0.0001523781,0.00000246146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002665485,"about_ca_system_score_gemma":0.0003253842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.160643e-7,"about_ca_topic_score_gemma":8.4711e-8,"domain_scores_codex":[0.9983957,0.00008264387,0.0006593021,0.0003082788,0.0003094664,0.000244651],"domain_scores_gemma":[0.9984506,0.00003954709,0.0006324148,0.0002733081,0.0004154509,0.0001886778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002290687,0.0002928864,0.003368905,0.0002315049,0.00006615255,0.000005109236,0.00003655743,0.00004499331,0.9951856,0.000001074846,0.0004928763,0.00004534256],"study_design_scores_gemma":[0.0005986917,0.0002455794,0.0001683942,0.0001640469,0.00002858961,0.00001276664,0.0001317958,0.000002932545,0.9975342,0.00001621618,0.000876972,0.0002197919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9761769,0.003914197,0.01950561,0.0000198141,0.0001202099,0.0001466356,0.00004778769,0.000008206104,0.00006071293],"genre_scores_gemma":[0.9957194,0.00007165478,0.003424854,0.00004060477,0.0002393642,0.000008424397,0.0003159556,0.00002681976,0.0001528746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01954261,"threshold_uncertainty_score":0.7809657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211180974874958,"score_gpt":0.2260588940356639,"score_spread":0.2139470842869143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}