{"id":"W2080870167","doi":"10.1634/stemcells.2007-0248","title":"Pluripotentiality and Conditional Transgene Regulation in Human Embryonic Stem Cells Expressing Insulated Tetracycline-ON Transactivator","year":2007,"lang":"en","type":"article","venue":"Stem Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Leukemia and Lymphoma Society","keywords":"Biology; Transactivation; Transgene; Embryonic stem cell; Cell biology; Gene; Gene expression; Germ layer; Molecular biology; Regulation of gene expression; Computational biology; Genetics; Induced pluripotent stem cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002569503,0.0003038096,0.0001543896,0.0002188288,0.0001389445,0.0003814183,0.0002757782,0.0002191234,0.000869316],"category_scores_gemma":[0.0001655789,0.000173583,0.0002542846,0.0001758835,0.0003272631,0.0002041718,0.0003376984,0.000635243,0.0003530111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002045761,"about_ca_system_score_gemma":0.0002850028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004062505,"about_ca_topic_score_gemma":0.0006947562,"domain_scores_codex":[0.9995829,0.00006931287,0.00006374953,0.00006733087,0.0001863224,0.00003035688],"domain_scores_gemma":[0.9998511,0.00002522124,0.00003989497,0.00003802266,0.00002454422,0.00002120271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001144794,0.000006826866,0.00006932598,0.00002168002,0.00000258492,0.00004083588,0.00001340305,0.00006407468,0.9986544,0.0001951064,0.0000268563,0.0008934331],"study_design_scores_gemma":[0.000005447902,0.00009664938,0.001118333,0.000005150793,0.00001056547,0.0002654096,0.00001195932,0.000721266,0.9942463,0.00004279777,0.003471354,0.000004762506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9189054,0.002810864,0.06964624,0.0002672363,0.0001155859,0.0002649443,0.001788935,0.0004089168,0.005791962],"genre_scores_gemma":[0.9563524,0.002451896,0.02963461,0.0001263905,0.00002810874,0.0001742206,0.002838468,0.0001240182,0.008269836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000869316,"threshold_uncertainty_score":0.002908111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01786756226094163,"score_gpt":0.2746160532490702,"score_spread":0.2567484909881286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}