{"id":"W2080879068","doi":"10.1007/s004250100581","title":"Isolation and partial characterization of norcoclaurine synthase, the first committed step in benzylisoquinoline alkaloid biosynthesis, from opium poppy","year":2001,"lang":"en","type":"article","venue":"Planta","topic":"Plant tissue culture and regeneration","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Benzylisoquinoline; Papaveraceae; Papaver; Chemistry; Alkaloid; Stereochemistry; Sanguinarine; Enzyme kinetics; Biochemistry; Elicitor; Enzyme; Biosynthesis; Biology; Botany; Active site","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001220045,0.0004652809,0.0003900955,0.0002769706,0.0002424376,0.0004019417,0.0002522779,0.0002960127,0.0003687701],"category_scores_gemma":[0.0002805898,0.000211445,0.000289235,0.0002970718,0.0003187326,0.0003051446,0.0003032263,0.0006497765,0.0003680682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003488132,"about_ca_system_score_gemma":0.0005337915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002920054,"about_ca_topic_score_gemma":0.003350619,"domain_scores_codex":[0.999935,0.000005793968,0.000005273265,0.00001583159,0.00001967451,0.00001845264],"domain_scores_gemma":[0.999742,0.00006433689,0.00003796083,0.00004463126,0.00004652247,0.00006459017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005627062,0.000009910186,0.0004021921,0.00003353564,0.000004198959,0.0001015112,0.00002458922,0.00004832182,0.9978684,0.00007849825,0.00001831352,0.001354252],"study_design_scores_gemma":[0.00002505236,0.0001375995,0.03882039,0.00001258145,0.00006251415,0.001396935,0.0001374178,0.001085386,0.9501967,0.0003549164,0.007751148,0.00001934922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850643,0.00272296,0.00790392,0.0004228554,0.00002956232,0.0000418786,0.002066123,0.00006125731,0.001687132],"genre_scores_gemma":[0.9781085,0.002149585,0.005376936,0.0001334317,0.00003014221,0.00003760339,0.008914148,0.00005746499,0.005192178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002920054,"threshold_uncertainty_score":0.005806088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009361036393038407,"score_gpt":0.2102557359158878,"score_spread":0.2008946995228494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}