{"id":"W2080916540","doi":"10.1074/jbc.m802834200","title":"Initiation of Mammalian O-Mannosylation in Vivo Is Independent of a Consensus Sequence and Controlled by Peptide Regions within and Upstream of the α-Dystroglycan Mucin Domain","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bruker (Canada)","funders":"","keywords":"Consensus sequence; Upstream (networking); Mucin; Sequence (biology); Biology; Dystroglycan; Domain (mathematical analysis); Peptide; Computational biology; Peptide sequence; Cell biology; Genetics; Computer science; Biochemistry; Gene; Laminin; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001702901,0.0003018873,0.0001572838,0.00009084379,0.0001330513,0.0002086216,0.00008721268,0.0001448165,0.0005267273],"category_scores_gemma":[0.0001433766,0.0001340055,0.0001752325,0.00007732795,0.0002223896,0.0001576529,0.0002235135,0.0003307841,0.000310689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001953468,"about_ca_system_score_gemma":0.0001889343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002666514,"about_ca_topic_score_gemma":0.0005597352,"domain_scores_codex":[0.9998968,0.00002425729,0.000007765483,0.00002852326,0.00001901843,0.00002367796],"domain_scores_gemma":[0.9998204,0.00005009641,0.00005585051,0.00002678868,0.00001425195,0.00003256642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003625138,0.000004577482,0.0001080966,0.00000794103,0.000001610394,0.00001808219,0.000006695933,0.0000194634,0.9993697,0.00005011496,0.000004632532,0.000372929],"study_design_scores_gemma":[0.000007149943,0.0001670741,0.004191504,0.000003399824,0.000007028709,0.0002102685,0.00001477963,0.000461448,0.9939726,0.00003966631,0.0009225078,0.000002702698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949143,0.000548769,0.003712488,0.00001809197,0.00000630689,0.00001797979,0.00005697369,0.00004136115,0.0006837404],"genre_scores_gemma":[0.9949063,0.0004162076,0.003444406,0.00002156714,0.000004410052,0.00001931303,0.0003178063,0.00001907378,0.0008509408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005267273,"threshold_uncertainty_score":0.001762092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01754271061029247,"score_gpt":0.2417024011593367,"score_spread":0.2241596905490442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}