{"id":"W2080916540","doi":"10.1074/jbc.m802834200","title":"Initiation of Mammalian O-Mannosylation in Vivo Is Independent of a Consensus Sequence and Controlled by Peptide Regions within and Upstream of the α-Dystroglycan Mucin Domain","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bruker (Canada)","funders":"","keywords":"Consensus sequence; Upstream (networking); Mucin; Sequence (biology); Biology; Dystroglycan; Domain (mathematical analysis); Peptide; Computational biology; Peptide sequence; Cell biology; Genetics; Computer science; Biochemistry; Gene; Laminin; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002275245,0.00008934019,0.0002846917,0.00001708834,0.00002714171,0.000001343559,0.00009298009,0.0001883397,0.00001085731],"category_scores_gemma":[0.0002183207,0.00005750865,0.00008043915,0.00005219697,0.0004592624,0.000003059099,0.00004141336,0.000120636,1.500324e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000680958,"about_ca_system_score_gemma":0.00006329977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002155932,"about_ca_topic_score_gemma":0.000007248863,"domain_scores_codex":[0.9991546,0.00008937222,0.0004742273,0.0001176366,0.00008345446,0.00008072318],"domain_scores_gemma":[0.9991109,0.00005009395,0.0006010388,0.0001021766,0.00009806225,0.00003776875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009276471,0.00007780825,0.06109046,0.00002866568,0.00003384869,0.000002330941,0.0001173557,0.00002668881,0.9375493,0.00001878753,0.0001082129,0.00001890765],"study_design_scores_gemma":[0.002852597,0.0003667204,0.02344597,0.00004771491,0.00001650901,0.0001257438,0.0004647103,0.00001808245,0.9718242,0.0007415285,0.00002603315,0.00007023131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990408,0.0004534722,0.00002307906,0.0001821916,0.000012511,0.00008512573,0.00003859846,6.754249e-7,0.0001634933],"genre_scores_gemma":[0.9995081,0.0002591858,0.0001340086,0.00004722769,0.00001698888,0.00000194798,0.000006088022,0.000002692441,0.00002372047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03764449,"threshold_uncertainty_score":0.2345135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01754271061029247,"score_gpt":0.2417024011593367,"score_spread":0.2241596905490442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}